BACE2 inhibition aggravates the metabolic consequences of a high-fat diet in mice

by Fundació Clínic per a la Recerca Biomèdica

Type 2 diabetes (DM2) and obesity are closely linked. A study conducted by researchers from CIBERDEM and IDIBAPS has demonstrated that the absence of the protease BACE2 (β-site APP-cleaving enzyme 2)...

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New plasma biomarker to detect Alzheimer’s disease in Down syndrome individuals

by Hospital de la Santa Creu i Sant Pau

​International collaboration led by researchers at the Sant Pau Reseach Institute – IIB Sant Pau in Barcelona, Spain, shows effectiveness of a plasma biomarker to detect Alzheimer’s Disease in D...

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Researchers demonstrate the presence of stable beta-amyloid dimers in the brains of patients with Alzheimer’s disease

by IRB Barcelona - Instituto de Investigación Biomédica

A study headed by IRB Barcelona provides the first direct evidence of beta-amyloid dimers (two proteins joined together) in patients with Alzheimer’s disease and points to the potential of these mol...

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New strategy to obtain a specific type of amyloid-beta aggregate that may underlie neuronal death in Alzheimer’s disease

by IRB Barcelona - Instituto de Investigación Biomédica

Researchers at IRB Barcelona describe for the first time how to prepare a specific type of aggregate of the amyloid-beta protein with the ability to perforate the cell membrane. What causes neuron dea...

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Epigenetic alterations in Alzheimer’s disease, nature vs. nurture on the path to dementia

by Professional Newco

Nowadays there are still people that believe in destiny. However the scientific community more and more is bringing light to that subject showing that although the genetic material could program ourse...

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