Mapping the genomic and immune landscapes of metastatic disease: new opportunities for personalized therapy against breast cancer

by Vall d’Hebron

5 years ago
personalized therapies, cancer, metastases, breast cancer, immuno-based therapies, multi-platform analysis

Extensive multi-platform analysis of multiple breast cancer metastases paves the way for developing novel personalized therapies. This present study provides new insights into metastatic cell spread...

Liquid biopsy: ‘classifier’ of metastatic breast cancer subgroups

by VHIO

5 years ago
liquid biopsy, breast cancer, diagnostic techniques

Metastatic breast cancer (MBC) is a heterogeneous and highly complex disease for which there is a critical need to identify novel biomarkers towards more effectively and precisely guiding treatment de...

CNIO researchers confirm links between aggressive prostate cancer and hereditary breast cancer

by CNIO - Centro Nacional de Investigaciones Oncológicas

5 years ago
BRCA2, prostate, prostate cancer, ovarian cancer, breast cancer

Published in the Journal of Clinical Oncology, the study has potential implications for families with members suffering from these two types of tumours who are at an increased risk of developing cance...

CRG projects have been awarded ERC Proof of Concept grants

by Centre for Genomic Regulation

6 years ago
breast cancer, pneumonia, IMPACCT, MycoVAP

IMPACCT and MycoVAP projects both will receive ERC PoC grants to explore potential clinical applications of their recent results on breast cancer and pneumonia respectively.

Mapping tumour development

by IRB Barcelona - Instituto de Investigación Biomédica

6 years ago
breast cancer, metastasis, “la Caixa” Foundation

Roger Gomis, ICREA researcher at the Institute for Research in Biomedicine (IRB Barcelona), and head of the Growth Control and Cancer Metastasis lab, has been awarded funding from the “la Caixa” F...

Tumour cells evade death through in extremis DNA repair

by IRB Barcelona - Instituto de Investigación Biomédica

6 years ago
DNA damage, breast cancer, p38 inhibitors

A study on breast cancer conducted at IRB Barcelona identifies the key role of p38 in safeguarding tumour cells against the excessive accumulation of DNA damage, which would otherwise cause cell death...

Exposure to common THM levels in drinking water not associated with breast cancer

by ISGlobal - Instituto de Salud Global de Barcelona

6 years ago
trihalomethanes, water, breast cancer

Exposure to trihalomethanes (THMs) in residential water is not associated with an increased risk of breast cancer. This is the main conclusion of a new study by the Barcelona Institute for Global Heal...

Researchers identify a protein that keeps metastatic breast cancer cells dormant

by IRB Barcelona - Instituto de Investigación Biomédica

6 years ago
metastatic cells, latent state, breast cancer, MSK1

A team of scientists headed by Roger Gomis at IRB Barcelona reveals one of the mechanisms that allows metastatic cells to leave a latent state.

A study reveals the biological changes in breast cancer between the primary tumor and metastases

by Fundació Clínic per a la Recerca Biomèdica

7 years ago
metastases, breast cancer

A study published in the journal Cancer Research underscores the importance of the molecular characterization of the metastases in breast cancer. Researchers have described, for the first time, that t...

Bioinformatics brings to light new combinations of drugs to fight breast cancer

by IRB Barcelona - Instituto de Investigación Biomédica

7 years ago
bioinformatics analysis, breast cancer, drugs, resistance

A bioinformatics analysis of pairing 64 drugs used to treat breast cancer allows researchers at IRB Barcelona to identify 10 previously untested combinations with potential to tackle resistance to bre...

Hospital Clínic will implement a new genomic test to predict response to treatment in breast cancer

by Fundació Clínic per a la Recerca Biomèdica

8 years ago
genomic test, chemotherapy, breast cancer, third generation test, test PAM50

Researchers from Hospital Clínic and IDIBAPS lead an international study in which they have developed a genomic test to predict the response to chemotherapy in breast cancer. Hospital Clínic of Barc...

La Masia and the AECC promoting a solidarity oil for breast cancer research

by Vall d’Hebron

8 years ago
AECC, La Masia, cáncer de mama, breast cancer

The Spanish Association Against Cancer (AECC) and La Masía have presented today the initiative "Aceite de Oliva Solidario" (Solidarity Olive Oil). The goal of the challenge – which starts today and...