How to industrialize cell and gene therapies?

by Pall Biotech

4 years ago
Accelerator℠, cell, seminar, gene therapies, manufacturing challenges, potential solutions

As gene therapies move towards commercialization, a robust, scalable and affordable manufacturing process is critical to ensure these novel therapies reach the patient and that a pipeline of clinical ...

Secrets of the internal human cell cytoskeleton revealed

by Centre for Genomic Regulation

4 years ago
Microtubules, cell, cytoskeleton

In a new study published in the journal Developmental Cell, researchers at the Centre for Genomic Regulation (CRG) describe how human cells stimulate the production of microtubules, a fundamental b...

IBEC researchers explain 'Durotaxis', a cell migration mechanism with a potential role in several diseases

by IBEC - Institut de Bioenginyeria de Catalunya

4 years ago
Durotaxis, cell, tissue, diseases

Xavier Trepat, group leader of the “Integrative cell and tissue dynamics” at IBEC together with Raimon Sunyer, Senior researcher in Trepat’s lab, have written a Primer in Current Biology magazin...

Aglaris Secures Major Funding to Drive Commercialisation of Ground- breaking Cell-based Therapy Manufacturing System

by CRB Inverbío SA SGECR

5 years ago
therapy, Aglaris, cell, gene

Aglaris Ltd, the innovator in cell therapy manufacturing, has been awarded three prestigious grants totalling over €2million to advance its breakthrough technologies towards commercialisation.

CAR T-cell therapy

by Asphalion

5 years ago
CAR, cell, cancer, therapy

While the success of autologous chimeric antigen receptors (CAR) T-cell medicines cannot be denied, with the recent approvals of Kymriah (tisagenlecleucel) and Yescarta (axicabtagene ciloleucel) pavin...

Excessive DNA replication and its potential use against cancer

by CNIO - Centro Nacional de Investigaciones Oncológicas

7 years ago
proteins, DNA re-replication, cell, cell malignancy, cancer

Simultaneous over-expression of two proteins provokes DNA re-replication in some cell types. This phenomenon can lead to cell malignancy but also might be used to attack cancer cells

Cells move en masse towards rigid tissues

by Institut de Bioenginyeria de Catalunya

8 years ago
cell, collective intelligence, cancer, rigid tissues

The researchers developed a theory explaining the phenomenon, naming it collective durotaxis. “Each cell applies a force to its environment that allows it to measure the surrounding stiffness. But c...