The ch-TOG protein is essential for building and maintaining the cell skeleton

by IRB Barcelona - Instituto de Investigación Biomédica

1 year ago
cytoskeleton, ch-TOG protein, tubulin, centrosomes

ch-TOG cooperates with a microtubule initiating complex, thus favouring the formation of new microtubules, when the cell is not dividing.

Self-assembled fibrillar networks arranged as a simple model of cytoskeletons induce complex functional responses

by Universidad de Santiago de Compostela

2 years ago
cytoskeleton, simple molecules, CiQUS

The cytoskeleton constitutes a network of filaments that gives shape and resistance to cells, representing a major element in key functions as cell motility and division.

Scientists from the CNIO and IRB Barcelona assemble the γ-tubulin ring complex in vitro for the first time

by CNIO - Centro Nacional de Investigaciones Oncológicas

3 years ago
electron cryomicroscopy, cytoskeleton, γTuRC, CNIO, IRB Barcelona

Researchers from the Microtubule Organization lab, headed by Jens Lüders at IRB Barcelona, and the Macromolecular Complexes in DNA Damage Response Group, led by Oscar Llorca at the Spanish National C...

When feeling the pinch, nuclei instigate cells to escape crowded spaces

by Centre for Genomic Regulation

4 years ago
cytoskeleton, cells, pinch, crowded spaces

The threat of serious deformation triggers a rapid escape reflex that enables cells to move away and squeeze out of tight spaces or crowded tissues.

Secrets of the internal human cell cytoskeleton revealed

by Centre for Genomic Regulation

4 years ago
Microtubules, cell, cytoskeleton

In a new study published in the journal Developmental Cell, researchers at the Centre for Genomic Regulation (CRG) describe how human cells stimulate the production of microtubules, a fundamental b...

DGK ζ is key for actin cytoskeleton remodelling at the B cell immune synapse

by Centro Nacional de Biotecnología (CNB)

4 years ago
protein, cytoskeleton, immune

DGK (diacylglycerol kinases) are proteins known for their role as negative regulators of the immune response of B and T lymphocytes. For this reason, they are under study as therapeutic targets for th...

Mechanical forces control cell fate during brain formation

by UPF - Universitat Pompeu Fabra

5 years ago
neurons, brain, cytoskeleton

The study shows that during the embryonic development of the brain, the cells that are between adjacent segments detect the mechanical forces generated during morphogenesis to regulate the balance bet...

The cytoskeleton of neurons has been found to be involved in Alzheimer’s disease

by Universidad del País Vasco

5 years ago
cytoskeleton, neurons, Alzheimer's, dendritic spines

A researcher at the UPV/EHU-University of the Basque Country has participated in the study into the impairment of the dynamics of spines that receive information from other neurons

CNIO finds the origin of a type of thrombocytopenia caused by an oncogene

by CNIO - Centro Nacional de Investigaciones Oncológicas

6 years ago
MASTL protein, cytoskeleton, thrombocytopenia

This work has allowed to understand, through the study of MASTL protein, the molecular origin of inherited thrombocytopenia in some patients and to successfully explore therapeutic options on a mouse ...