A study makes a significant contribution to progress in gene therapy efficiency by identifying the source of asymmetry in RNA-DNA hybrids

by IRB Barcelona - Instituto de Investigación Biomédica

5 years ago
DNA, RNA, gene therapies, asymmetry between nucleic acid hybrid

Modesto Orozco’s laboratory (IRB Barcelona) has published a study on the source of asymmetry between nucleic acid hybrid (RNA and DNA) in CHEM (Cell Press). The results are a promising step towards...

A new extinct chimpanzee lineage discovered in bonobo DNA

by UPF - Universitat Pompeu Fabra

5 years ago
chimpanzee, DNA, bonobo, species

Researchers from the Institute of Evolutionary Biology have discovered a new branch of archaic chimpanzees, extinct today, that crossed with bonobos around half a million years ago.

Las tres etapas principales de la expresión de genes están conectadas

by Agencia Sinc

5 years ago
genes, células, proteínas, DNA, ARN

Gracias a la regulación que lleva a cabo la proteína Xrn1, las tres etapas principales de la expresión de genes están conectadas. Se trata de un sistema de seguridad en nuestras células que las h...

Testing fish DNA: a cost effective way to tackle fraud

by European Commission - Joint Research Centre

5 years ago
marine enviroment, DNA, Testing fish

A new study shows that authorities can reap the benefits of investing in fish DNA analysis techniques to enforce EU laws and protect sustainable fishing activities.

Gold nanoparticles to facilitate in-situ detection of amplified DNA at room temperature

by ICN2 Instituto Catalán de Nanociencia y Nanotecnología

5 years ago
temperature, nanoparticles, DNA, RPA

The proposed nanobiosensor developed by ICN2 Nanobioelectronics and Biosensors Group led by ICREA Prof. Arben Merkoçi and Vetgenomics takes advantage of the high sensitivity achieved when using gold ...

The novel method Nested CRISPR enables efficient genome editing using long DNA fragments

by IBEC - Institut de Bioenginyeria de Catalunya

5 years ago
CRISPR, biomedical research, genome, DNA

CRISPR is a technique that is revolutionizing biomedical research through high-precision genome editing. However, even though it allows the creation or correction of mutations consisting of a singl...

Niosomes, efficient DNA delivery vehicles for gene therapy of the central nervous system

by Universidad del País Vasco

5 years ago
ADN, neurons, glial cells, therapeutic plasmids, Niosomes, DNA

The NanoBioCel group of the UPV/EHU-University of the Basque Country has developed some lipid vesicles that have been shown to transfer genetic material efficiently and viably

El correcto empaquetamiento del genoma es esencial para mantener su estabilidad

by Universidad Autónoma de Madrid

6 years ago
genoma, cromatina, DNA

La estructura de la cromatina en la que se empaqueta nuestro genoma juega un papel fundamental para coordinar los procesos de replicación del DNA y transcripción. Así lo describen en Nature Communi...

Celebrating DNA International Day

by Life Length

6 years ago
DNA, genetics

A paper published in the journal Nature drew the attention of international scientific community on April 25, 1953. James Watson, Francis Crick, Maurice Wilkins, Rosalind Franklin and several colleagu...

Does it exist a link between stem cells and telomeres?

by Life Length

6 years ago
telomeres, DNA, iPS cells, telomerase

In 2009, Elizabeth Blackburn, Jack Szostak and Carol Greider received the Nobel Prize in Medicine for the discovery of the role of telomeres as DNA protectors and activators of the enzyme “telomeras...

The isoforms of the HP1 protein differentially regulate the organization and structure of heterochromatin

by IBEC - Institut de Bioenginyeria de Catalunya

7 years ago
HP1 proteins, chromatin, genome, DNA

Researchers from the Epigenetics and Cancer Biology Program of the Bellvitge Biomedical Research Institute (IDIBELL), led by Dr. Àlex Vaquero, have elucidated the role of HP1 proteins in relation to ...

Link between defects in DNA replication and loss of heterochromatin

by Centre for Genomic Regulation

7 years ago
cell division, epigenetics, DNA

Scientists reveal that a fault in the process that copies DNA during cell division can cause epigenetic changes that may be inherited for up-to five generations. They also identified the cause of thes...