25 years studying the immune system

by IrsiCaixa

The IrsiCaixa AIDS Research Institute celebrates its 25th anniversary as an international center of reference in the field of HIV and infectious diseases. The research at IrsiCaixa is now expanding to...

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Predicting the response of HIV-infected individuals to checkpoint inhibitor immunotherapy

by UPF - Universitat Pompeu Fabra

Scientists led by Andreas Meyerhans and Gennady Bocharov have designed a mathematical model to predict the response of HIV-infected individuals to a type of cancer immunotherapy.

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WHO recommends an integrase inhibitor as preferred HIV treatment option in all populations

by Fundació Bancària 'la Caixa'

The WHO Guideline Development Group decided to recomment dolutegravir as the preferred first-line and second-line treatment for all populations, in contrast with initial studies.

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Mathematicians calculate the number of immune cells needed to thwart HIV progress

by UPF - Universitat Pompeu Fabra

In the future, a model of this kind will enable scientists to carry out computer experiments for the development of vaccines and medicines for infectious diseases. The study, led by Russian researcher...

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IrsiCaixa develops antibodies that block one of the internalization pathways of the Ebola virus into human cells

by IrsiCaixa

The study demonstrates that the receptor Siglec-1 is used by different virus, such as Ebola, Marburg and HIV, to enter the myeloid cells and develops novel antibodies against this protein.

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Paradigm shift in how bone fractures are avoided in HIV patients

by IMIM - Institut Hospital del Mar d'Investigacions Mèdiques

The discovery modifies how the problem of bone fracture is addressed in these patients, leading the way to studies of new drugs that complement treatments for combatting the virus

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The Worldwide Response to the HIV/AIDS Pandemic Since 1981. Lessons Learned

by ISGlobal - Instituto de Salud Global de Barcelona
  • 2 years ago
  • HIV

How did we go from 270 reported cases of AIDS in the United States in 1981 to 37 million people living with HIV worldwide in 2017? What did we do right and what could we have done better?

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A study unravels new stem cell transplant factors that might lead to HIV eradication in the body

by IrsiCaixa

The article shows for the first time that stem cell source, time to achieve full replacement of recipient cells with donor cells and graft-versus-host reactivity might contribute to HIV eradication. T...

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Membrane receptors do not act alone

by Centro Nacional de Biotecnología (CNB)

A study shows that the CXCR4 chemokine receptors form aggregates in the cell membrane to be activated and carry out their function. This aggregation process is regulated by the presence of a ligand, b...

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A biomarker for monitoring tuberculosis treatment responses in HIV-Positive patients

by ISGlobal - Instituto de Salud Global de Barcelona

IP10 kinetics during the first week of TB treatment is associated with bacteriological confirmation at diagnosis in HIV-positive patients, according to a new study led by ISGlobal, an institution supp...

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A protein in blood could facilitate HIV diagnosis and treatment follow-up in low-income countries

by ISGlobal - Instituto de Salud Global de Barcelona

A simple blood test to determine levels of the IP-10 protein in blood could represent a key tool in the diagnosis of recently infected HIV individuals that have not yet developed virus-specific antibo...

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Launch of a clinical trial that will evaluate new therapies to prevent tuberculosis in persons with HIV

by ISGlobal - Instituto de Salud Global de Barcelona

People living with HIV have a higher risk of developing tuberculosis (TB). In order to prevent TB in these patients, the WHO recommends a daily dose of isoniazid (6H) treatment during six months. Howe...

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