The EMBO Journal. A new mechanism that explains the toxicity of USP7 inhibitors, which are under development for the treatment of cancer, unveiled

by CNIO - Centro Nacional de Investigaciones Oncológicas

​The researchers have discovered that USP7 inhibitors -under development by several pharmaceutical companies for the treatment of cancer- trigger a premature activation of cell cycle proteins, leadi...

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RAD51 as a biomarker in extending PARP inhibitors to additional tumor subtypes

by VHIO

Thanks to continued progress in more precisely defining tumor subtypes and thus achieving an increasingly in-depth understanding of the complex biological systems that underlie cancer development, cur...

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