BBRC researchers identify new tau biomarkers to detect the preclinical phase of Alzheimer’s disease

by Fundación Pasqual Maragall

​An international study led by the research center of the Pasqual Maragall Foundation, the Barcelonaβeta Brain Research Center (BBRC), promoted by the “la Caixa” Foundation, has analyzed a

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IRB Barcelona opens new laboratory focused on targeted protein degradation as a therapeutic tool

by Parc Científic de Barcelona

Scientist Cristina Mayor-Ruiz joins the Institute for Research in Biomedicine (IRB Barcelona) to lead the new Targeted Protein Degradation and Drug Discovery Lab. Along with the addition of this group...

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Dsup, a protein unique to tardigrades, protects DNA from radiation: How does it do it?

by Centro de Biotecnología y Genómica de Plantas CBGP

​The outstanding ability of tardigrades to survive environmental extremes has attracted an enormous attention in biology and biotechnology

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A new mechanism of toxicity in Alzheimer's disease 
revealed by the 3D structure of Aβ protein assemblies

by IRB Barcelona - Instituto de Investigación Biomédica

Researchers led by Natàlia Carulla find that specific amyloid-beta (Aβ) protein ensembles have the capacity to disrupt the membrane of neurons, causing their death. The results have been publishe...

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Researchers identify a fundamental protein to guarantee liver regeneration

by Universitat de Barcelona

Researchers from the Faculty of Medicine of the University of Barcelona and the CELLEX Biomedical Research Centre from IDIBAPS, in collaboration with scientists from the University of Sydney, Universi...

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DGK ζ is key for actin cytoskeleton remodelling at the B cell immune synapse

by Centro Nacional de Biotecnología (CNB)

DGK (diacylglycerol kinases) are proteins known for their role as negative regulators of the immune response of B and T lymphocytes. For this reason, they are under study as therapeutic targets for th...

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Discovered a small protein that synchronizes the circadian clocks in shoots and roots

by CRAG

The CSIC researcher Paloma Mas leads a study published in Nature Plants demonstrating that the clock protein ELF4 moves in synch with temperature to coordinate rhythms in shoots and roots.

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DRUG TARGETS: The heat shock protein 90 inhibitor ganetespib failed to improve outcomes when added to chemotherapy in advance NSCLC (phase III GALAXY-2 trial). Samples were obtained for biomarker studies; results not yet reported

by OncoDNA

Randomized Phase III Study of Ganetespib, a Heat Shock Protein 90 Inhibitor, With Docetaxel Versus Docetaxel in Advanced Non–Small-Cell Lung Cancer (GALAXY-2)

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Experts in G protein-coupled receptors meet at the UB to discuss new pharmacological perspectives

by Hospital Universitari de Bellvitge

Within the framework of the X Esteve Foundation Discussion Group, on February 13th and 14th the tenth meeting of the working group on new advances in the field of G-protein coupled receptors (GPCR) wa...

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Identifican el mecanismo que desencadena un tipo raro de distrofia muscular

by Universitat Autònoma de Barcelona (UAB)

A study led by the IBB-UAB has identified the molecular mechanism through which a protein, when carrying genetic mutations associated with a rare disease known as limb-girdle muscular dystrophy, type ...

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New aspects of Globular Glial Tauopathy could help in the design of more effective drugs against this dementia

by Hospital Universitari de Bellvitge

Tau is not the only protein implicated in protein inclusion formation responsible for this neurodegenerative disease.

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