ORYZON Launches Pioneering Schizophrenia Precision Medicine Study In Collaboration With Columbia Psychiatry

by Oryzon Genomics

Goal is to characterize the neuropsychiatric symptoms of patients harboring disease-causing SETD1A gene mutations Also includes fundamental research in preclinical SETD1A models

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The lack of interaction between two neuronal receptors is a determining factor in schizophrenia

by Universitat de Barcelona

Schizophrenia is a severe neuropsychiatric disorder which is presented through hallucinations, delusions and behavioural and motor disorders. Historically, this disease was associated with an overacti...

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ORYZON initiates a new project to explore the efficacy of vafidemstat in the treatment of schizophrenia

by Oryzon Genomics

Oryzon Genomics, S.A. (ISIN Code: ES0167733015, ORY), a clinical-stage biopharmaceutical company leveraging epigenetics to develop therapies in diseases with strong unmet medical need, announced today...

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Significant differences exist among neurons expressing dopamine receptors

by Universitat Autònoma de Barcelona (UAB)

An international collaboration, which included the involvement of the research team from the Institut de Neurociències (INC) and from the Department of Cellular Biology, Physiology and Immunology, ha...

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Experts in G protein-coupled receptors meet at the UB to discuss new pharmacological perspectives

by Hospital Universitari de Bellvitge

Within the framework of the X Esteve Foundation Discussion Group, on February 13th and 14th the tenth meeting of the working group on new advances in the field of G-protein coupled receptors (GPCR) wa...

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Biological diagnosis of schizophrenia: the future

by Fundació Clínic per a la Recerca Biomèdica

Schizophrenia is a very heterogeneous disease, patients who suffer this may present a variety of symptoms. In addition, there is currently no analytical or imaging test that confirms the diagnosis. Th...

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Advances in the study of drugs to combat cognitive impairment in schizophrenia

by Universidad del País Vasco

The UPV/EHU-University of the Basque Country is proposing improvements with respect to the pharmacological study of cognitive function enhancers in patients with schizophrenia

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Describen alteraciones en estructuras cerebrales en pacientes con esquizofrenia descubiertas mediante un innovador análisis de imagen cerebral

by Cibersam- Centro de Investigación Biomédica en Red de Salud Mental

Para intentar clarificar el tipo de anomalías estructurales cerebrales presentes en la esquizofrenia, se ha llevado a cabo un innovador meta-análisis prospectivo que analiza datos de imagen cerebral...

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Un modelo matemático predice la esquizofrenia en el primer brote psicótico

by Cibersam- Centro de Investigación Biomédica en Red de Salud Mental

Según los resultados obtenidos, empleando un simple análisis de sangre y una técnica de laboratorio fácil y barata es posible realizar la predicción utilizando la actividad aminopeptidásica como...

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New international tool to evaluate and classify schizophrenia

by Universitat de Barcelona

It is an instrument that provides a framework to measure health concerning, for instance, diagnosis, patient functioning, disability levels or the reasons to contact health services

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'Spark', a new public-private project created to develop a drug to fight the cognitive impairment associated with schizophrenia

by IRB Barcelona - Instituto de Investigación Biomédica

The expected end-result will be the obtaining of an optimal formulation and a route of administration of the compound for its use as a drug in patients. This will allow carrying out the regulatory pre...

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Functional connectivity dynamics, a new biomarker of some mental diseases

by UPF - Universitat Pompeu Fabra

The authors of the study have also shown that optimized computational models by adapting to the average time of functional connectivity have not been able to capture these spontaneous transitions of f...

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