Los efectos positivos y negativos de las drogas psicodélicas se podrían separar para crear antidepresivos, según un estudio

by CSIC - Centro Superior de Investigaciones Científicas

Un grupo de investigación muestra que la plasticidad neuronal y las alucinaciones de drogas como el LSD están causados por receptores neuronales diferentes y, por tanto, se pueden separar

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Avanzan en la identificación de nuevas rutas de señalización y dianas terapéuticas para patologías neurodegenerativas como la enfermedad de Huntington

by CIBERER - Centro de Investigación Biomédica en Red de Enfermedades Raras

Han descubierto que la liberación de una señal hormonal, desde unas neuronas sensoriales del gusano C. elegans, denominadas ASJ, modula la actividad del receptor nuclear NHR-1, encargado de regular ...

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Unleashing splicing to understand biology and eventually tackle ‘untreatable’ diseases

by Centre for Genomic Regulation

Cells use editing tools to skip or rearrange information stored in DNA. Thanks to a 10-million-euro ERC Synergy Grant co-financed by ERC and UKRI, researchers have today launched a new project to stud...

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Investigadores del ISQCH abren la puerta a la posibilidad de diseño de nuevos fármacos

by Universidad de Zaragoza

Los resultados de esta investigación son clave para poder explorar el reconocimiento molecular entre los receptores biológicos del organismo y los puntos activos de los fármacos, posibilitando la p...

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Un nuevo anticuerpo conjugado podría ser útil para personalizar el tratamiento de pacientes con cáncer epitelial de ovario recurrente que expresan la proteína FolRα

by Vall d’Hebron

Los resultados del estudio fase I STRO-002 de expansión de dosis del fármaco luveltamab tazevibulin (luvelta) demuestran beneficios clínicos significativos en pacientes con cáncer de ovario con ex...

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A novel treatment combination shows promise as first-line treatment in patients with metastatic castration-resistant prostate cancer

by VHIO

Results from the Phase III TALAPRO-2 trial demonstrate that the combination of talazoparib plus enzalutamide vs. standard treatment of enzalutamide plus placebo significantly improves progression-free...

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CONTACT-03: underscoring the need to identify new treatment strategies in metastatic renal cancer after disease progression with prior immunotherapy

by VHIO

The data obtained in the study in which VHIO participated underline the importance of prospective evaluation of re-exposure to immunotherapy before it is adopted as a standard of care.

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More than Half of Malaria Infections During Pregnancy Are Undetectable by Microscopy

by ISGlobal - Instituto de Salud Global de Barcelona

Results of a meta-analysis of 68 studies in 27 countries have implications for the management and prevention of malaria during pregnancy, as well as for malaria elimination efforts

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New guidelines for the prevention, diagnosis and treatment of hepatocellular carcinoma

by Fundació Clínic per a la Recerca Biomèdica

The IDIBAPS researcher Josep M. Llovet has participated in the new American AASLD guidelines for the treatment of hepatocellular carcinoma, the most common type of liver cancer.

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Strabismus as the first symptom of severe congenital disorders

by DBGen Ocular Genomics

Strabismus is the first symptom of congenital cranial dysinnervation disorders such as Moebius and Duane among others. However, this trait is followed by more serious symptoms such as facial paralysis...

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The Cima University of Navarra and the high school Weizmann of Sciences sign a agreement of research against cancer

by Universidad de Navarra

Both centers initiate three pioneering biomedical projects combining artificial intelligence, cutting-edge technology Genetics and advanced therapies

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Methylation affects how proteins work. A new technique developed at CNIO shows why

by CNIO - Centro Nacional de Investigaciones Oncológicas

Protein methylation is a carefully controlled process that occurs in all living things, from the smallest bacteria to humans. Thanks to methylation, embryonic stem cells can develop into the different...

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