The most common type 2 diabetes drug needs the action of a cellular-stress-response protein to make effect

by Universitat de Barcelona

Metformin, the most prescribed drug for treating diabetes mellitus, known as type 2 diabetes, requires the presence of the growth differentiation factor 15 (GDF15) —a protein whose expression increa...

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Researchers uncover the mechanism of action of an important transcription factor

by IRB Barcelona - Instituto de Investigación Biomédica

Scientists at IRB Barcelona detail the DNA binding mechanism of FoxH1, a protein involved in embryonic development and in some tumour processes.

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CNIO researchers discover how to predict the efficacy of one of the most widely used drugs against breast cancer

by CNIO - Centro Nacional de Investigaciones Oncológicas

The CNIO group analyzed HER2-negative breast cancer samples from 130 patients treated with paclitaxel, one of the most widely used drugs against breast, ovarian, lung, bladder, prostate, melanoma, eso...

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A new atlas unveils which mutations are behind the noxious amyloid formation

by IBEC - Institut de Bioenginyeria de Catalunya

Researchers from the Institute for Bioengineering of Catalonia (IBEC) have developed the most complete atlas up to date with the genetic mutations that causes the formation of amyloid beta fibril, a p...

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Artificial Intelligence challenges in Medical Devices

by AKRN Scientific Consulting

Artificial intelligence (AI) is constantly bringing improvements to the field of medical devices, with AI technology being embedded in software used as a medical device or being a medical device by it...

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Claves de la braquiterapia de mama

by Alma Medical Imaging

La braquiterapia de mama está indicada, sobre todo, para casos de cáncer de mama en los que el tumor no es muy grande y en los que no hay afectación de los ganglios linfáticos.

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Identifiquen dos biomarcadors en pacients amb esclerosi lateral amiotròfica (ELA)

by Hospital de la Santa Creu i Sant Pau

L;os pacientes con esclerosis lateral amiotrófica (ELA) presentan niveles anormalmente elevados de las proteínas NOD2 y Spp1, por lo que estas moléculas se postulan como nuevos biomarcadores en la ...

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A biomarker in a blood test makes it possible to diagnose Alzheimer’s disease

by Fundació Clínic per a la Recerca Biomèdica

A study by the hospital Clínic Barcelona-IDIBAPS, published in the journal Neurology, confirms the usefulness of a blood-based biomarker to diagnose Alzheimer’s disease without the need for more in...

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Pulmobiotics receives 1.9m euros to develop ‘living medicine’ for lung cancer

by Centre for Genomic Regulation

Researchers at Pulmobiotics, a start-up founded in 2020 at the Centre for Genomic Regulation (CRG) in Barcelona, have begun work on a ‘living medicine’ to improve the efficacy of lung cancer treat...

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Identifican una estrategia terapéutica efectiva contra un subtipo de melanoma que actualmente no tiene tratamiento

by Universitat Rovira i Virgili

Uno de los subtipos más comunes de melanoma es causado por mutaciones en NRAS, una proteína relacionada con la malignidad de las células que se halla alterado en un 25% de los casos. Su tratamiento...

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ORYZON presents final data from Phase IIa ALICE trial in unfit AML patients with first-line treatment of iadademstat and azacitidine in oral presentation at ASH-2022

by Oryzon Genomics

Oryzon Genomics presents the final data from its Phase IIa ALICE trial, investigating iadademstat in combination with azacitidine in elderly or unfit patients with acute myeloid leukemia (AML), at the...

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Molecular hydrogen as a new strategy for the treatment of chronic pain

by Hospital de la Santa Creu i Sant Pau

The Molecular Neuropharmacology research group, coordinated by Olga Pol at the Sant Pau Biomedical Research Institute and the UAB Institute of Neurosciences, is looking for new therapeutic possibiliti...

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