Una combinación de señales en las histonas salvaguarda la información epigenética durante la división celular

by Centro Nacional de Biotecnología (CNB)

Las histonas regulan la organización del ADN a lo largo del ciclo celular. Modificaciones en estas proteínas determinan el grado de compactación del material genético y la expresión de sus genes....

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Study identifies a new therapeutic tool for child cancer

by Vall d’Hebron

The group of Translational Research in Child and Adolescent Cancer, led by Dr. Josep Sanchez de Toledo and Dr. Soledad Gallego in the Vall d'Hebron Research Institute (VHIR), has identified a microRNA...

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The detection of a genetic alteration in blood samples predicts resistance to treatment in metastatic prostate cancer

by Fundació Clínic per a la Recerca Biomèdica

The detection of TMPRSS2-ERG in the blood of patients with resistant metastatic prostate cancer predicts resistance to taxanes, such as docetaxel, and may be useful for selecting the best treatment op...

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Made of Genes busca 600.000 euros para acelerar su proyecto y desembarcar en Europa

by La Vanguardia

La startup, que forma parte de la aceleradora Wayra busca 600.000 euros de financiación en el segmento de business angels del sector médico, para acelerar el proyecto y desembarcar en Europa.

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EntreChem's mithralog EC-8042 promising activity for Ewing sarcoma, published in Clinical Cancer Research

by EntreChem

Collectively, these results provide a basis for the continued development of EC-8042 as an EWS-FLI1 inhibitor for the clinic, and highlights the therapeutic opportunities offered by targeting transcri...

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Barcelona, in the spotlight of bioinformatics and computational biology

by Centre for Genomic Regulation

From today until Wednesday 6th April, Barcelona hosts the Next Generation Sequencing (NGS) Conference for second consecutive time. The event, which will be focused on genome annotation, is organized b...

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Nuevos avances en el tratamiento de la Neuropatía Óptica Hereditaria de Leber

by Universidad Autónoma de Madrid

Investigadores de la UAM han demostrado que 3 mutaciones simultáneas en la Neuropatía Óptica Hereditaria de Leber (LHON), evento descrito por primera vez, provocan la misma disfunción que una sola...

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CNIO scientists discover a new mechanism of resistance to chemotherapy

by CNIO - Centro Nacional de Investigaciones Oncológicas

Óscar Fernández-Capetillo’s team reports that ATR kinase inhibitors are more effective in cells with high levels of CDC25A protein expression. ATR inhibitors were previously developed at the CNIO ...

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A key gene in the development of coeliac disease has been found in ‘junk' DNA

by Universidad del País Vasco

Science has published the study in which three researchers of the UPV/EHU-University of the Basque Country have participated. 40% of the population carry the main risk factor for coeliac disease but o...

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Thousands of genes from the umbilical cord change their activity in response to amniotic sac infection in preterm birth

by UPF - Universitat Pompeu Fabra

Genes that decreased their concentration, on the other hand, are mainly involved in fetal development, particularly brain development, and provide clues on possible molecular mechanisms leading to bra...

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Las consecuencias de una mala ‘digestión’ celular en el párkinson

by Fundación Andaluza para la Divulgación de la Innovación y el Conocimiento

Investigadores del laboratorio de Neurobiología celular del Instituto de Parasitología y Biomedicina López-Neyra (CSIC) en Granada han descubierto que el gen LRRK2 bloquea la autofagia, es decir, e...

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New members and focus on the CRG Business Board

by Centre for Genomic Regulation

CRG Technology and Business Development Office has redefined its priorities and the way it brings innovative ideas to the market, launching several new programs and activities to promote commercializa...

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