Minoryx Therapeutics – a drug development company specialized in the discovery and development of new drugs for orphan diseases, which has R& D laboratories at the Barcelona Science Park– announce...
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In epigenetics, there there are “accents”, called DNA methylation, which means having a C or a methyl-C. The first one usually means that a gene is expressed and active, while the second one impli...
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Different forms of the DIDO protein regulate activation of the differentiation process in embryonic stem cells. Advances in regenerative medicine require a closer look at stem cell biology and the mol...
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Investigadores del CIMA de la Universidad de Navarra demuestran que el bloqueo combinado de las proteínas C5a y PD-1 inhibe el crecimiento del tumor y previene las metástasis en modelos animales.
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New study shows that the protein c-Fos is necessary for liver carcinogenesis. The authors suggest that maintaining healthy cholesterol levels in the organism is therefore important for preventing live...
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Dado que HSF1 se perfila como una diana atractiva de nuevos agentes antitumorales que actúen inhibiendo su actividad, nuestro grupo de investigación se embarcó en la búsqueda de moléculas que inh...
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Mutaciones en el gen PLD3 producen pérdida de la función de los lisosomas, lo que activa procesos de muerte celular. La investigación liderada por el CSIC se ha llevado a cabo en nuevos modelos de ...
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In the most recent issue of Gastroenterology, a prestigious scientific journal in the area of gastrointestinal and liver diseases, researchers at the Center for Applied Medical Research (CIMA) of the ...
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Investigadores del IDIBAPS han identificado una nueva vía por la que las células cancerígenas evitan sus propios mecanismos anti-tumorales. Mediante estudios en células y en modelos animales de c...
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Un equipo español ha identificado una proteína del “esqueleto celular” como nuevo gen protumoral. Los resultados permiten proponer dianas terapéuticas para tumores altamente invasivos como los ...
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The authors describe how the overexpression of AURKA (Aurora kinase A, a protein involved in cell cycle control) is associated with a worse prognosis in patients with cutaneous melanoma. The expressio...
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The study concluded that ClC-2 (chloride channel), GlialCAM and MLC1 proteins (the latter two are altered in MLC) associate to form a ternary complex when astrocytes are depolarized, such as in situat...
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The research team observed changes in head circumf...
AtCDF3 gene induced greater production of sugars a...
Un estudio con datos de los últimos 35 años, ind...
En nuestro post hablamos sobre este interesante tipo de célula del...
Investigadores del Cima Universidad de Navarra constatan que la combin...
