isoCNV: in silico optimization of copy number variant detection from targeted or exome sequencing data

por Sequentia Biotech SL

Background: Accurate copy number variant (CNV ) detection is especially challenging for both targeted sequencing (TS) and whole‐exome sequencing (WES) data.

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Investigation of Nasal/Oropharyngeal Microbial Community of COVID-19 Patients by 16S rDNA Sequencing

por Sequentia Biotech SL

Since December 2019, SARS-CoV-2 infection has been still rapidly spreading, resulting in a pandemic, followed by an increasing number of cases in countries throughout the world. The severity of the di...

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Disruption of paternal circadian rhythm affects metabolic health in male offspring via nongerm cell factors

por Sequentia Biotech SL

Circadian rhythm synchronizes each body function with the environment and regulates physiology. Disruption of normal circadian rhythm alters organismal physiology and increases disease risk.

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An anchored chromosome-scale genome assembly of spinach improves annotation and reveals extensive gene rearrangements in euasterids

por Sequentia Biotech SL

Spinach (Spinacia oleracea L.) is a member of the Caryophyllales family, a basal eudicot asterid that consists of sugar beet (Beta vulgaris L. subsp. vulgaris), quinoa (Chenopodium quinoa Willd.), and...

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The impact of chromosomal fusions on 3D genome folding and recombination in the germ line

por Sequentia Biotech SL

The spatial folding of chromosomes inside the nucleus has regulatory effects on gene expression, yet the impact of genome reshuffling on this organization remains unclear.

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Phytotherapics in COVID19: Why palmitoylethanolamide?

por Sequentia Biotech SL

At present, googling the search terms “COVID‐19” and “Functional foods” yields nearly 500,000,000 hits, witnessing the growing interest of the scientific community and the general public in ...

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New tools for plant health discovering the power of omics

por Sequentia Biotech SL

​ Walter Sanseverino (CEO and co-founder) shared some of our exciting agricultural biotech projects, as part of BIOVEGEN’s Biotech Attraction event, including: gene expression for biostimulants...

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The potential of cannabidiol in the COVID‐19 pandemic

por Sequentia Biotech SL

Identifying drugs effective in the new coronavirus disease 2019 (COVID‐19) is crucial, pending a vaccine against SARS‐CoV2.

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Transcriptome-wide expression profiling of Sporothrix schenckii yeast and mycelial forms and the establishment of the Sporothrix Genome DataBase

por Sequentia Biotech SL

Sporothrix schenckii is a dimorphic fungus existing as mould in the environment and as yeast in the host. The morphological shift between mycelial/yeast phases is crucial for its virulence, but the tr...

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Comprehensive characterization of HBV in tumor and non-tumor liver tissues from patients with HBV related-HCC

por Sequentia Biotech SL

Infection with HBV is associated with a high risk of developing hepatocellular carcinoma (HCC). HBV may contribute to HCC development through both direct and indirect mechanisms. However, it remains u...

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Whole genome SNPs discovery in Nero Siciliano pig

por Sequentia Biotech SL

Autochthonous pig breeds represent an important genetic reserve to be utilized mainly for the production of typical products.

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Two Chloroflexi classes independently evolved the ability to persist on atmospheric hydrogen and carbon monoxid

por Sequentia Biotech SL

Most aerobic bacteria exist in dormant states within natural environments. In these states, they endure adverse environmental conditions such as nutrient starvation by decreasing metabolic expenditure...

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