Identifican una vía para evitar la resistencia al principal tratamiento de uno de los cánceres de mama más agresivos

by IMIM - Institut Hospital del Mar d'Investigacions Mèdiques

3 years ago
Neuregulina, Cancer

Médicos e investigadores del Hospital del Mar y del Instituto Hospital del Mar de Investigaciones Médicas, del CIBERONC y de dos centros de investigación italianos, han validado la relación entre ...

A master regulator gene for brain cancer with the worst prognosis

by CNIO - Centro Nacional de Investigaciones Oncológicas

3 years ago
genetic, Brain Tumour, Cancer

FOSL1, a gene that wasn’t previously related to brain tummors, acts as a general genetic switch for the mesenchymal subtype of glioblastoma

Machine learning fuels personalised cancer medicine

by IRB Barcelona - Instituto de Investigación Biomédica

3 years ago
cancer, tumour

The Biomedical Genomics laboratory at IRB Barcelona has developed a computational tool that identifies cancer driver mutations for each tumour type. This and other developments produced by the same l...

Profesionales demuestran que el riesgo de desarrollar leucemia mieloide aguda depende de la presencia de variaciones genéticas en genes del sistema inmune

by Hospital Universitario Virgen de las Nieves

3 years ago
inmunoterapia, investigación de Genética de Hemopatías Malignas, leucemia mieloide aguda, Cáncer

Este hallazgo, publicado en la prestigiosa revista científica Blood Cancer, podría ayudar a diseñar nuevos tratamientos basados en la inmunoterapia.

IDIBELL and ICO participate in the discovery of a weakness that could be used to treat defective cancers for SMARCA4

by Hospital Universitari de Bellvitge

3 years ago
protein SMARCA4, Cancer, Oncobell, Molecular Mechanisms, Oncology Program

The study suggests that tumors with a genetically inactivated form of the chromatin remodeling protein SMARCA4 are highly sensitive to inhibitors of the KDM6 family of histone demethylases.

Scientists from the ibs.GRANADA show that the risk of developing acute myeloid leukemia depends on the presence of genetic variations in genes of the immune system

by Instituto de Investigación Biosanitaria - Ibs Granada

3 years ago
Malignant Hemopathies, Genetics, myeloid leukemia, cancer

The Genetics of Malignant Hemopathies research group at ibs.GRANADA has shown that certain variations in genes of the immune system influence the risk of developing acute myeloid leukemia. These alter...

Eight CSIC biomedical projects receive 6.5 million euros from the CaixaResearch aid program

by CSIC - Centro Superior de Investigaciones Científicas

3 years ago
Health Research, CaixaResearch, neurological diseases, Cancer, infectious diseases, cardiovascular diseases

Eight researches led by or with the participation of scientists from the Spanish National Research Council (CSIC) have been selected by the “la Caixa” Foundation among the 30 projects of the Caixa...

Cancer and dementia research projects funded by the 'la Caixa' Foundation

by Centre for Genomic Regulation

3 years ago
cancer, dementia, new therapeutic

The “la Caixa” Foundation has funded two research projects at the Centre for Genomic Regulation (CRG) which aim to identify new therapeutic targets for cancer and develop new prevention strateg...

To die or not to die in response to stress, a decision regulated by MK2 protein levels

by IRB Barcelona - Instituto de Investigación Biomédica

3 years ago
stress conditions, cancer, proteins

Researchers at IRB Barcelona unveil a pathway that determines the fate of cells in response to stress conditions and identify an important mechanism that recovers cell balance.

PNAS. CNIO researchers clarify the role of the two isoforms of KRAS, the most common oncogene in human cancer

by CNIO - Centro Nacional de Investigaciones Oncológicas

3 years ago
KRAS, cancer, tumours, metastasis

KRAS was one of the first oncogenes to be identified, a few decades ago. It is among the most common drivers of cancer and its mutations can be detected in around 25 per cent of human tumours. The dev...

Cellular push and pull, a key to the body's response to processes such as cancer

by Fundació Clínic per a la Recerca Biomèdica

3 years ago
cancer, Research, Pneumology

Researchers from IDIBAPS, IBEC, UB and CIBERES discover how force dynamics affect cells and living tissues. The results give an insight into the critical mechanical processes that occur in different d...

A new approach to metastatic melanoma discovered

by IMIM - Institut Hospital del Mar d'Investigacions Mèdiques

3 years ago
BRAF oncogene inhibitors, chemotherapy, Cancer, metastatic melanoma, skin cancer

Combining chemotherapy and BRAF oncogene inhibitors is a very effective strategy for fighting metastatic melanoma, the leading cause of death from skin cancer in the world.