Myriad Obtains CE Mark for Tumor BRACAnalysis CDx(TM) and Launches Test in Europe as Companion Diagnostic for PARP Inhibitors

by Myriad Genetics Iberia

9 years ago
Tumor BRACAnalysis CDx test, cancer, BRCA1 or BRCA2 genes, Lynparza, ovarian cancer

Myriad is actively collaborating with leading pharmaceutical companies to develop Tumor BRACAnalysis CDx as a companion diagnostic for use with certain PARP inhibitors, platinum-based drugs and other ...

The first 'molecular labels' that predict the organs where metastases will form

by CNIO - Centro Nacional de Investigaciones Oncológicas

9 years ago
metastasis, cancer, exosomes, integrins proteins

The finding is considered one of the most important advances for over a century in addressing the challenge of predicting where tumor metastases will occur

Un modelo preclínico consigue la mayor similitud con los casos clínicos reales en inmunoterapia contra el cáncer

by Clínica Universidad de Navarra

9 years ago
modelo preclínico, cáncer, inmunología, inmunoterapia, células tumorales, Cancer Research

El estudio sobre el uso de células inmunológicas y tumorales humanas en la investigación preclínica, obra de investigadores de la Clínica y del CIMA, ha sido portada del primer ejemplar de septie...

Clínica Universidad de Navarra y CIMA: en marcha 25 ensayos clínicos de inmunoterapia contra diferentes tipos de cáncer

by Clínica Universidad de Navarra

9 years ago
cáncer, inmunoterapia, ensayos clínicos

Son centros de referencia en esta modalidad de tratamiento, que ya ha constatado resultados positivos en melanoma avanzado, subtipos de cáncer de pulmón, tumores de cabeza y cuello, de hígado y de ...

Ability Pharmaceuticals announces positive Phase 1/1b study results of ABTL0812 in cancer patients with advanced solid tumors

by AbilityPharma

9 years ago
cancer, ABTL0812, drug development, advanced solid tumors

Study confirms that ABTL0812 is extremely well tolerated and shows promising signs of clinical antitumor activity. The results will be presented at AACR-NCI-EORTC International Conference on Molecular...

The CNIO discovers a link between a rare form of anemia and cancer

by CNIO - Centro Nacional de Investigaciones Oncológicas

9 years ago
Diamond-Blackfan anaemia, cancer, p53 gene, protein RPL11

CNIO researchers have discovered that mice with partial deficiency of RPL11 (i.e. one of the two copies of the gene is faulty) not only suffer from the incorrect generation and maturation of red blood...

Identifican una estrategia antitumoral en la terapia contra el cáncer

by Universidad de Málaga

9 years ago
cáncer, enzima glutaminasa, leucemias linfoblásticas agudas de células T, proteína Notch1

El trabajo, publicado en la revista Nature Medicine, propone la inhibición selectiva de la glutaminolisis, una ruta metabólica esencial en muchos tipos de cáncer

Descubren un nuevo mecanismo inmune contra el cáncer

by Centro Nacional de Investigaciones Cardiovasculares - CNIC

9 years ago
proteína AID, cáncer

El equipo dirigido por la Dra. Almudena R Ramiro ha identificado un mecanismo por el cual el sistema inmune es capaz de reconocer células epiteliales que acumulan mutaciones y daño en el DNA, impidi...

Desarrollan un nanodispositivo, calentador y termómetro a la vez, con aplicaciones en el tratamiento contra el cáncer

by Universidad de Zaragoza

9 years ago
hipertermia magnética, cancer

Supone un gran avance en la terapia de hipertermia magnética utilizada en patalogía oncológica y en el estudio del transporte de calor a escala nanométrica

Defective telomeres are now being linked to dozens of diseases

by CNIO - Centro Nacional de Investigaciones Oncológicas

9 years ago
telomeres, cancer, aging

Two CNIO researchers have published a detailed review on what is known today about the structures that protect the ends of chromosomes. Telomeres are key elements in ageing and cancer and much more co...

3D review on Smads

by IRB Barcelona - Instituto de Investigación Biomédica

9 years ago
Smad proteins, cancer

Maria Macias, Pau Martín, and Joan Massagué publish a featured review article in Trends in Biochemical Sciences (TIBS) on the Smad protein family, the members of which play a key role in cancer

Studying the environmental chemicals to assess their long-term carcinogenic potential

by Vall d’Hebron

9 years ago
environmental chemicals, cancer

Tumor formation is induced by cells that are able to avoid senescence to become immortal. “We have to study combinations of chemicals in each type of cell in order to understand which combinations a...