Scientists find a new molecular mechanism involved in the development of cancer

by UPF - Universitat Pompeu Fabra

8 years ago
RBPs, cancer, DNA, alternative splicing

The Computational Genomics research group at Pompeu Fabra University has discovered new alterations linked to cancer and has revealed the importance of transcriptome in the development of tumours.

CNIO scientists have discovered a code of signals that regulates genome duplication

by CNIO - Centro Nacional de Investigaciones Oncológicas

8 years ago
SUMOylations, USP7, DNA

The balance between two modifications in proteins — ubiquitination and SUMOylation — regulates cellular DNA copying. The USP7 protein travels with the machinery required to copy the DNA and favour...

CNIO scientists use the Internet network theory to decipher the first epigenetic communication network

by CNIO - Centro Nacional de Investigaciones Oncológicas

8 years ago
Internet network theory, epigenetics, DNA, stem cells, cancer

The scientists employed the algorithms used to analyse the influence and popularity of websites, such as Wikipedia or social networks. These results provide the basis for exploring communication betwe...

Researchers find out cause of mutations which are not in genetic material

by IBEC - Institut de Bioenginyeria de Catalunya

8 years ago
cancer, proteins, DNA, gene ADAR1

The gene identified (referred ADAR1) regulates the level of mutations in RNA, and it is a publisher gene. People with an excess of this gene have an imbalance in the composition of this molecule just ...

Cut & paste is now for DNA dark matter too

by Centre for Genomic Regulation

9 years ago
DNA, CRISPR-Cas9, genome, dark matter

Researchers from the Centre for Genomic Regulation have adapted the most revolutionary genome-editing technique to DNA dark matter, too.

Nanoparticles simplify DNA identification and quantification

by Universitat Autònoma de Barcelona (UAB)

9 years ago
DNA, nanoparticles, Leishmania infantum

In an article published in Small, researchers successfully applied a new qualitative and quantitative method for the detection of a DNA sequence characteristic of Leishmania infantum kinetoplast, a fr...

Discovered the sixth DNA's base?

by IBEC - Institut de Bioenginyeria de Catalunya

9 years ago
methyl-adenine, DNA

More complex cells called eukaryotes such as the human body cells, also present the sixth DNA base. These studies suggest that algae, worms and flies possess mA and it acts to regulate the expression ...