Researchers describe molecular mechanism involved in Huntington's neurodegeneration

by Universitat de Barcelona

Protein alteration in the family of lamins causes several diseases, known as laminopathies, such as progeria or precocious ageing.

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Researchers design a new family of molecules with high affinity to join altered receptors in neurodegenerative diseases

by Universitat de Barcelona

An article published in the Journal of Medicinal Che​mistry shows a new family of molecules with high affinity to join imidazoline receptors, which are altered in the brain of those patients with ne...

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Researchers identify a molecular mechanism involved in neuronal degeneration caused by Huntington’s disease

by Universitat de Barcelona

Researchers from the Institute of Neurosciences of the University of Barcelona (UB​Neuro) and the August Pi i Sunyer Biomedical Research Institute (IDIBAPS) described a mechanism, the increase of pr...

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A new molecular mechanism could explain the origins of the depressive symptoms in Huntington’s disease

by Universitat de Barcelona

The new study, published in the journal Biological Psychiatry, sheds light on the design of future pharmacological strategies –based on the modelling of specific molecular pathways- to treat depress...

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The messenger in Huntingon's disease

by Centre for Genomic Regulation

A research effort led by Eulàlia Martí at the Centre for Genomic Regulation reveals new molecular mechanisms of Huntington’s disease. The results, recently published in The Journal of Clinical Inv...

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Strengthening gene therapy for Huntington’s disease

by Centre for Genomic Regulation

Huntington’s disease is a genetic disorder that affects around 1 in every 10,000 people and damages nerve cells in the brain. This causes neurological symptoms affecting movement, cognition and beha...

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Researchers discover new applications of the drug fingolimod to improve cognitive deficits in Huntington’s disease

by Fundació Clínic per a la Recerca Biomèdica

Fingolimod, a drug used to treat multiple sclerosis, restores hippocampal synaptic plasticity and improves memory function

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Primer fármaco epigenético cuyos efectos beneficiosos se transmiten a la descendencia, en un modelo animal para el Huntington

by Revista Genética Médica

El equipo, dirigido por Elisabeth Thomas, observó alteraciones de la expresión de genes implicados en la metilación del ADN tanto en fibroblastos de pacientes con enfermedad de Huntington como en u...

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