Researchers at IRB Barcelona identify a protein that protects against non-alcoholic fatty liver disease

by IRB Barcelona - Instituto de Investigación Biomédica

Work headed by scientist Antonio Zorzano proposes a possible therapeutic target to treat fatty liver, a disease for which there is currently no treatment. The study, which was done in collaboration w...

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Nature: The protein p38gamma identified as a new therapeutic target in liver cancer

by Centro Nacional de Investigaciones Cardiovasculares - CNIC

CNIC scientists have shown for the first time that a protein related to cell stress also regulates cell division

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New mechanisms to fight against melanoma metastasis

by IRB Lleida. Institut de Recerca Biomèdica

The UdL participates in an international investigation published in "Cell"

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Researchers from the CNIO and the Hospital 12 de Octubre make sense out of the chaos of melanoma

by CNIO - Centro Nacional de Investigaciones Oncológicas

The study has discovered that numerous processes involved in the metastasis of melanoma, which were thought to be independent from each other, have a global coordinator: the p62 protein. The publicati...

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Proteins can transfer electrons at a distance

by Institut de Bioenginyeria de Catalunya

Collaborating IBEC groups have published a study in Nature Communications that reveals that electron transfer can take place while a protein is approaching its partner site, and not only when the prot...

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New insights in the role of protein N-glycosylation in root development

by Centro de Biotecnología y Genómica de Plantas CBGP

Plant roots have the potential capacity to grow almost indefinitely if meristematic and lateral branching is sustained. We have identified a novel and viable allele of LEW3 called limited root growth ...

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IBEC at the forefront of research in mechanobiology

by Institut de Bioenginyeria de Catalunya

During the last two decades, advances in our understanding of these mechanisms have allowed researchers to find out more about cell-generated forces at different scales, ranging from molecular forces ...

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Researchers at CIMA describe that XBP1 could be a key agent in avoiding the accumulation of mutations

by CIMA - Centro de Investigación Médica Aplicada

In the most recent issue of Gastroenterology, a prestigious scientific journal in the area of gastrointestinal and liver diseases, researchers at the Center for Applied Medical Research (CIMA) of the ...

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Inhibition of a specific protein prevents and reverses aortic aneurysm in models of Marfan syndrome and similar diseases

by Centro Nacional de Investigaciones Cardiovasculares - CNIC

Scientists at the Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC) and the Consejo Superior de Investigaciones Científicas (CSIC) have discovered that inhibition in mice of a pro...

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New computational method to create drugs more efficiently

by Universitat de Barcelona

This approach has been applied in software that identifies molecules with more possibilities to join the targeted protein. “The method allows selecting molecules that can be starting points to creat...

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Identification of a 'Plasmodium falciparum' protein domain that could play a key role in the development of severe malaria

by ISGlobal - Instituto de Salud Global de Barcelona

A protein expressed at the surface of red blood cells infected by Plasmodium falciparum could be a key player in the vascular pathology that leads to severe malaria by binding to the gC1qR receptor, a...

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Scientists at the CNIO have deconstructed one of the myths of biological innovation

by CNIO - Centro Nacional de Investigaciones Oncológicas

The study relegates 'alternative splicing' as a source of protein production to a secondary level, which calls for rethinking the biology of higher organisms. The team argues that most human genes pro...

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