A study from Lleida identifies mechanisms that allow the detection of Alzheimer's risk in people with schizophrenia

by IRB Lleida. Institut de Recerca Biomèdica

4 months ago
schizophrenia, Alzheimer, extracellular vesicles (EVs)

The research lays the groundwork for the future validation of a blood test aimed at estimating this risk of dementia

Innovative research project investigates how our brain makes decisions

by Fundació Clínic per a la Recerca Biomèdica

11 months ago
schizophrenia, obsessive-compulsive disorder (OCD), dopamine

Using functional magnetic resonance imaging (fMRI), the researchers plan to collect the largest dataset to date on indecisiveness in OCD and jump to conclusions in schizophrenia.

Differences between men and women in the effects of genetic risk of schizophrenia

by Universitat de Barcelona

1 year ago
schizophrenia, schizotypy

According to the dimensional view of mental disorders, psychosis is expressed on a continuum ranging from mild subclinical traits and experiences present in the general population (schizotypy) to clin...

ORYZON announces formal grant of key European patent for vafidemstat

by Oryzon Genomics

2 years ago
borderline personality disorder (BPD), schizophrenia, Vafidemstat, EP3661510B1

Oryzon announced today that the European Patent Office (EPO) has now formally granted Oryzon’s European patent EP3661510B1, titled “Methods of treating behavior alterations” related to vafidemst...

New Avenues to Developing Personalized Treatments for Schizophrenia

by IMIM - Institut Hospital del Mar d'Investigacions Mèdiques

2 years ago
G proteins, 2A serotonin receptor, Schizophrenia

It has been demonstrated, for the first time, the role of two proteins in the activation and deactivation of the system through which drugs act against schizophrenia symptoms. These two proteins are p...

A genomic study will help to predict which patients with schizophrenia might benefit from early treatment with clozapine

by Hospital de la Santa Creu i Sant Pau

3 years ago
clozapine, polygenic risk, schizophrenia

It has been bring to the table a novel genomic tool that would help to predict which patients will respond poorly to conventional treatments and, therefore, would be early candidates for treatment wit...

People with schizophrenia who participate in clinical trials may not be representative of the population suffering from this disease

by Instituto de Investigación e Innovación Parc Taulí

4 years ago
schizophrenia

An international study led by I3PT notes that clinical trials may account for only about one-fifth of people in the real world with schizophrenia spectrum disorders, and points out that new studies sh...

ORYZON enrolls first patient in EVOLUTION, a Phase IIb clinical trial with vafidemstat in schizophrenia

by Oryzon Genomics

5 years ago
Oryzon Genomics, EVOLUTION, Schizophrenia, Vafidemstat

Oryzon Genomics, S.A. (ISIN Code: ES0167733015, ORY), a clinical-stage biopharmaceutical company leveraging epigenetics to develop therapies in diseases with strong unmet medical need, announced today...

ORYZON receives approval to start EVOLUTION Phase IIb trial with vafidemstat in schizophrenia

by Oryzon Genomics

5 years ago
Vafidemstat, Oryzon Genomics, biopharmaceutical, Clinical Trial, schizophrenia

ORYZON Launches Pioneering Schizophrenia Precision Medicine Study In Collaboration With Columbia Psychiatry

by Oryzon Genomics

6 years ago
neuropsychiatric symptoms, Schizophrenia, Precision Medicine

Goal is to characterize the neuropsychiatric symptoms of patients harboring disease-causing SETD1A gene mutations Also includes fundamental research in preclinical SETD1A models

The lack of interaction between two neuronal receptors is a determining factor in schizophrenia

by Universitat de Barcelona

6 years ago
neuronal, schizophrenia, neuropsychiatric disorder, dopaminergic

Schizophrenia is a severe neuropsychiatric disorder which is presented through hallucinations, delusions and behavioural and motor disorders. Historically, this disease was associated with an overacti...