Are antidepressants overprescribed?

by Fundació Clínic per a la Recerca Biomèdica

1 year ago
antidepressants

There is a significant trend towards an increase in the “off-label” prescription of antidepressants in the primary care system of Catalonia; that is, in cases where the use of this medication has ...

Clínic-IDIBAPS researchers obtain insulin-producing cells from human fibroblasts

by Fundació Clínic per a la Recerca Biomèdica

1 year ago
reprogrammed fibroblasts, insulina, insuline

The method, published in the journal Communications Biology, enables direct transformation of skin fibroblasts into insulin-producing cells with a capacity to respond to glucose, introducing just five...

Cinco o más porros a la semana implican un consumo de cannabis de riesgo para la salud

by Fundació Clínic per a la Recerca Biomèdica

1 year ago
cannabis, THC

Un grupo de profesionales, coordinado por profesionales del Clínic-IDIBAPS expertos en adicciones, ha consensuado que el consumo de 5 o más porros a la semana implica un riesgo para la salud.

Identifican una forma severa de mpox con una elevada mortalidad en personas con VIH avanzado

by Fundació Clínic per a la Recerca Biomèdica

1 year ago
infecciones por mpox, VIH

Investigadores del Clínic-IDIBAPS han participado en una colaboración internacional que ha identificado casos de formas graves de mpox con una alta mortalidad en personas severamente immunodeprimida...

How does pregnancy affect a woman's brain?

by Fundació Clínic per a la Recerca Biomèdica

1 year ago
pregnancy, grey matter

A recent study indicates that changes can occur in the structure and function of a woman’s brain when she is pregnant. These changes may prepare the woman for the arrival of her baby.

Pain that can be mistaken for a heart attack

by Fundació Clínic per a la Recerca Biomèdica

1 year ago
heart attack

Pain in the heart area when caused by a heart attack produces a feeling of oppression in the chest. However, other conditions, such as anxiety, oesophageal reflux or muscle pain, can produce similar s...

Alterations in microRNAs are found with the potential to predict the progression of Parkinson’s disease

by Fundació Clínic per a la Recerca Biomèdica

1 year ago
miR-4505, miR-8069, miR-6125 and miR-451a, LRRK2 gene

Researchers at Clínic Barcelona-IDIBAPS have observed scans in the expression profile of four microRNAs that could help to detect the appearance of Parkinson’s disease and monitor its development i...

Myeloid cells play a key role in liver T cell reprogramming

by Fundació Clínic per a la Recerca Biomèdica

1 year ago
hepatocellular carcinoma., lipopolysaccharide (LPS), CD14+CD8+T cells, Myeloid cells

Researchers from Clínic Barcelona-IDIBAPS take part in a study, published by Nature, which describes the role that monocytes and macrophages play in reprogramming liver-resident CD8+ T cells and alte...

Temporarily replacing tacrolimus with prednisone enables safe, effective short-term treatment using ritonavir-boosted antivirals in solid organ transplant recipients with COVID-19

by Fundació Clínic per a la Recerca Biomèdica

1 year ago
tacrolimus, prednisone, ritonavir

Clínic Barcelona-IDIBAPS researchers have demonstrated that replacing the immunosuppressant drug tacrolimus with prednisone prevents the appearance of toxicity due to interaction with ritonavir.

What are the warning signs if you have constipation?

by Fundació Clínic per a la Recerca Biomèdica

1 year ago
Constipation

Constipation may occur occasionally, but can sometimes be chronic. It may be due to several causes, such as slow intestinal movement. However, it may also be indicative of a metabolic, digestive or ne...

A preclinical trial by the U.S. National Institutes of Health validates the efficacy of Uric Acid for ischaemic stroke

by Fundació Clínic per a la Recerca Biomèdica

1 year ago
cerebral ischaemia, Uric Acid

Uric Acid was shown to improve the prognosis of ischaemic stroke in a preclinical study carried out on rodents within the framework of the Stroke Preclinical Assessment Network (SPAN) in the USA, a ne...

Could obesity and type 2 diabetes be treated with probiotics?

by Fundació Clínic per a la Recerca Biomèdica

1 year ago
intestinal microbiota, probiotics

Obesity is an emerging global health problem and a significant risk factor for developing other diseases such as type 2 diabetes. It seems that imbalances in the microbiota and a decrease in certain i...