The definition of the metabolic characteristics of breast cancer opens the door to new therapeutic strategies

by Hospital Universitari de Bellvitge

An international study, with the participation of IDIBELL and ICO, determines that the metabolism of breast tumor cells is defined by their origin.

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The importance of DNA compaction in tissue formation

by IRB Barcelona - Instituto de Investigación Biomédica

​Researchers at IRB Barcelona identify that the expression of ancestral fragments of viral DNA results in a strong inflammatory response and causes breast tissue dysfunction.

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Descubren una conexión entre senescencia y células madre provocada por una proteína iniciadora del cáncer de mama

by CNIO - Centro Nacional de Investigaciones Oncológicas

El diagnóstico precoz y la mejora de los tratamientos del cáncer de mama han permitido disminuir su mortalidad en los últimos años, llegándose a situar los índices de supervivencia en el 85% a d...

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The CNIO participates in a study that defines the most important genes that increase the risk of breast cancer

by CNIO - Centro Nacional de Investigaciones Oncológicas

Genetic inheritance affects the likelihood of developing breast cancer. Some genes are already known to increase cancer risk; other genes are suspected to be involved, but not to what extent. It is cr...

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American Hospital of Paris and OncoDNA Partner to Advance Breast Cancer Patients Management

by OncoDNA

American Hospital of Paris and OncoDNA announced a new joint initiative that is intended to advance the use of precision medicine in routine clinical practice for patients with metastatic breast cance...

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BREAST CANCER Despite preclinical data identifying oncogenic RANK pathway activation, the RANK ligand inhibitor denosumab failed to improve outcomes in the neoadjuvant or adjuvant settings

by OncoDNA

Denosumab is a fully human monoclonal antibody that binds to, and inhibits, the receptor activator of RANKL (TNFSF11) and might affect breast cancer biology, as shown by preclinical evidence.

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Double the promise: two novel approaches set to transform the treatment landscape of HER2+ refractory metastatic breast cancer

by VHIO

Published in parallel in The New England Journal of Medicine*, data from two phase II studies presented yesterday at the San Antonio Breast Cancer Symposium – SABCS (10 – 14 December, San Anton

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CNIO boosts its top research lines in metastasis and DNA repair with the creation of three new research groups

by CNIO - Centro Nacional de Investigaciones Oncológicas

The new groups, led by researchers Felipe Cortés, Eva González-Suárez and Solip Park, join the more than 400 scientists who make up the Center to boost the basic and translational Molecular Oncolog...

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Mapping the genomic and immune landscapes of metastatic disease: new opportunities for personalized therapy against breast cancer

by Vall d’Hebron

Extensive multi-platform analysis of multiple breast cancer metastases paves the way for developing novel personalized therapies. This present study provides new insights into metastatic cell spread...

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Liquid biopsy: ‘classifier’ of metastatic breast cancer subgroups

by VHIO

Metastatic breast cancer (MBC) is a heterogeneous and highly complex disease for which there is a critical need to identify novel biomarkers towards more effectively and precisely guiding treatment de...

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CNIO researchers confirm links between aggressive prostate cancer and hereditary breast cancer

by CNIO - Centro Nacional de Investigaciones Oncológicas

Published in the Journal of Clinical Oncology, the study has potential implications for families with members suffering from these two types of tumours who are at an increased risk of developing cance...

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