Immunotherapy with genetically modified immune cells increases survival of patients with aggressive B lymphoma who do not respond to chemotherapy

by Hospital Universitari de Bellvitge

2 years ago
genetically modified, immune cells, aggressive B lymphoma, chemotherapy, CART cells

The use of genetically modified T lymphocytes (CART lymphocytes) to recognize cancer cells increases the life expectancy of patients with chemotherapy-resistant lymphoma.

Immune cell atlas of human cancers created for precision oncology

by Centre for Genomic Regulation

2 years ago
Genomic Regulation, immune cells, cellular atlas, tumour

Researchers at the Centro Nacional de Análisis Genómico (CNAG-CRG), part of the Centre for Genomic Regulation (CRG) in Barcelona, have created the first cellular atlas of the immune cells infiltr...

Breast cancer cells create collagen shields to protect themselves from the immune system

by Hospital Universitari de Bellvitge

3 years ago
immune cells, Breast cancer, mammary tumor

The high number of immune cells within tumors is an indicator of a good prognosis, since they attack the tumor and help destroy it.

IDIBELL scientists identify a key regulator of the acquisition of immune tolerance to tumor cells in cancer patients

by IBEC - Institut de Bioenginyeria de Catalunya

7 years ago
immune cells, epigenetics, cancer

Researchers of the Chromatin and Disease Group from the Bellvitge Biomedical Research Institute (IDIBELL) in Barcelona have identified a distinctive epigenetic event in immune cells that differentiate...

Cell 'canibalism' educates our defenses

by Centro Nacional de Investigaciones Cardiovasculares - CNIC

7 years ago
macrófagos, Phagocytosis, immune cells, macrophages

Phagocytosis is a biological mechanism whereby specialized cells ingest and degrade old, dead, or damaged cells to prevent tissue damage due to their accumulation. But phagocytosis appears to also hav...

CIC bioGUNE researchers identify immune cell checkpoints that regulate cell responsiveness to infectious agents

by CIC bioGUNE

8 years ago
mitochondrial MCJ protein, immune cells

The research describes the role of the mitochondrial MCJ protein in the metabolism of immune cells. The work, conducted in collaboration with the University of Vermont, has recently been published in ...