Cells are more resilient to environmental changes than previously thought

by IRB Barcelona - Instituto de Investigación Biomédica

The first study to evaluate how environmental conditions affect the genetic program underlying cellular survival, led by the University of Toronto, involves the collaboration of the Structural Bioinfo...

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A computational guide to lead cells down desired differentiation paths

by CIC bioGUNE

A novel computer-guided design tool predicts combinations of transcription factors for more effective engineering of cell types with potential use in cell therapies and tissue modeling.

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Predicting how brain cancer responds to immunotherapy non-invasively

by Centre for Genomic Regulation

The analysis of immune system cells in the cerebrospinal fluid can characterise and identify the types of cerebral metastasis that could respond to immunotherapy treatments.

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REAP: new strategy in cancer treatment

by Centro Singular de Investigación en Química Biológica y Materiales Moleculares

CiQUS will be involved in REAP, a newly European project to reveal drug tolerant persister cells by contrast enhanced multimodal optical imaging. BioNanoTools, the group led by Beatriz Pelaz, will dev...

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Cancer cells resistant to treatment are already present before diagnosis of adult leukaemia

by IRB Barcelona - Instituto de Investigación Biomédica

This work is a collaboration between Núria López-Bigas’ lab at IRB Barcelona and the groups headed by Anna Bigas (Hospital del Mar Medical Research Institute) and Josep Maria Ribera (Josep Carrera...

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Microrobots mobility and ionic strenght: theory and experiments reveal their relationship

by IBEC - Institut de Bioenginyeria de Catalunya

The group of ICREA Professor Samuel Sánchez at IBEC leads a work revealing that the self-propelled movement of microrobots depends on the amount of salts, called ionic strength, present in the liquid...

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When feeling the pinch, nuclei instigate cells to escape crowded spaces

by Centre for Genomic Regulation

The threat of serious deformation triggers a rapid escape reflex that enables cells to move away and squeeze out of tight spaces or crowded tissues.

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Igniting the synthetic transport of amino acids in living cells

by IRB Barcelona - Instituto de Investigación Biomédica

Diseases that stem from or are affected by defective amino acid transport, such as cancer, cystic fibrosis or neurodegenerative conditions, may benefit from advances in this field. The work, a coll...

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Recombination suppression in heterozygotes for a pericentric inversion induces the interchromosomal effect on crossovers in Arabidopsis

by Sequentia Biotech SL

During meiosis, recombination ensures allelic exchanges through crossovers (COs) between the homologous chromosomes. Advances in our understanding of the rules of COs have come from studies of mutatio...

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Improving European healthcare through cell-based interceptive medicine

by Centre for Genomic Regulation

Cells isolated from tissue are channeled into miniature chips for processing of individual cells. © Felix Petermann, MDC/LifeTime

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Nanoscale cellular adhesion is a key factor for cartilage production in vitro

by IBEC - Institut de Bioenginyeria de Catalunya

Researchers from the Institute of Bioengineering of Catalonia (IBEC) develop a methodology based on nanopatterned structures which improves the differentiation of mesenchymal stem cells into cartilage...

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Human body mostly composed of just five major groups of cell

by Centre for Genomic Regulation

Scientists around the world have today published the results of the third phase of the Encyclopedia of DNA Elements (ENCODE) in Nature. The international consortium of approximately 500 scientists con...

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