Self-assembled fibrillar networks arranged as a simple model of cytoskeletons induce complex functional responses

by Universidad de Santiago de Compostela

The cytoskeleton constitutes a network of filaments that gives shape and resistance to cells, representing a major element in key functions as cell motility and division.

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Scientists from the CNIO and IRB Barcelona assemble the γ-tubulin ring complex in vitro for the first time

by CNIO - Centro Nacional de Investigaciones Oncológicas

Researchers from the Microtubule Organization lab, headed by Jens Lüders at IRB Barcelona, and the Macromolecular Complexes in DNA Damage Response Group, led by Oscar Llorca at the Spanish National C...

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When feeling the pinch, nuclei instigate cells to escape crowded spaces

by Centre for Genomic Regulation

The threat of serious deformation triggers a rapid escape reflex that enables cells to move away and squeeze out of tight spaces or crowded tissues.

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Secrets of the internal human cell cytoskeleton revealed

by Centre for Genomic Regulation

In a new study published in the journal Developmen​tal Cell, researchers at the Centre for Genomic Regulation (CRG) describe how human cells stimulate the production of microtubules, a fundamental b...

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DGK ζ is key for actin cytoskeleton remodelling at the B cell immune synapse

by Centro Nacional de Biotecnología (CNB)

DGK (diacylglycerol kinases) are proteins known for their role as negative regulators of the immune response of B and T lymphocytes. For this reason, they are under study as therapeutic targets for th...

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Mechanical forces control cell fate during brain formation

by UPF - Universitat Pompeu Fabra

The study shows that during the embryonic development of the brain, the cells that are between adjacent segments detect the mechanical forces generated during morphogenesis to regulate the balance bet...

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The cytoskeleton of neurons has been found to be involved in Alzheimer’s disease

by Universidad del País Vasco

A researcher at the UPV/EHU-University of the Basque Country has participated in the study into the impairment of the dynamics of spines that receive information from other neurons

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CNIO finds the origin of a type of thrombocytopenia caused by an oncogene

by CNIO - Centro Nacional de Investigaciones Oncológicas

This work has allowed to understand, through the study of MASTL protein, the molecular origin of inherited thrombocytopenia in some patients and to successfully explore therapeutic options on a mouse ...

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