As gene therapies move towards commercialization, a robust, scalable and affordable manufacturing process is critical to ensure these novel therapies reach the patient and that a pipeline of clinical ...
In a new study published in the journal Developmental Cell, researchers at the Centre for Genomic Regulation (CRG) describe how human cells stimulate the production of microtubules, a fundamental b...
Xavier Trepat, group leader of the “Integrative cell and tissue dynamics” at IBEC together with Raimon Sunyer, Senior researcher in Trepat’s lab, have written a Primer in Current Biology magazin...
Aglaris Ltd, the innovator in cell therapy manufacturing, has been awarded three prestigious grants totalling over €2million to advance its breakthrough technologies towards commercialisation.
While the success of autologous chimeric antigen receptors (CAR) T-cell medicines cannot be denied, with the recent approvals of Kymriah (tisagenlecleucel) and Yescarta (axicabtagene ciloleucel) pavin...
Simultaneous over-expression of two proteins provokes DNA re-replication in some cell types. This phenomenon can lead to cell malignancy but also might be used to attack cancer cells
The researchers developed a theory explaining the phenomenon, naming it collective durotaxis. “Each cell applies a force to its environment that allows it to measure the surrounding stiffness. But c...