More than 20 years with HIV under control without treatment: what we know about exceptional elite controllers

by IrsiCaixa

3 months ago
HIV, T cells

Less viral reservoir, a strong HIV-specific response, and defective viruses are some of the key factors that allow these individuals to control HIV, representing a great model of functional cure for t...

Reviving a depleted immune system: an unmet goal for people on HIV treatment

by IrsiCaixa

1 year ago
TIGIT, immunotherapy, HIV

IrsiCaixa describes how the cells of the immune system decrease in people with HIV who have been on treatment for 10 years, and confirm the key role of TIGIT in this loss of defenses

Reduced HIV reservoir through combination of antiretroviral therapy and the anticancer drug dasatinib

by IrsiCaixa

3 years ago
chronic myeloid leukemia, anticancer drug, antiretroviral treatment, dasatinib, HIV

A study in which IrsiCaixa has participated shows that the anticancer drug dasatinib, in combination with antiretroviral treatment, reduces the reactivation ability and the size of the viral reservoir...

Update on HIV infection and the COVID-19 pandemic

by IrsiCaixa

3 years ago
HIV, Covid19, infection

In this video you can watch the course organised by the Chair in Infectious Diseases and Immunity UVIC-UCC, directed by Dr Clotet, in which all the information related to HIV infection and the COVID-1...

Therapeutic HIV vaccine achieves an immune response that improves viral control when antiretroviral treatment is interrupted

by IrsiCaixa

4 years ago
antiretroviral treatment, Infectious Diseases, vaccine, HIV

The HTI vaccine of AELIX Therapeutics, a spin-off of HIVACAT, shows in a Phase I/IIa clinical trial that 40% of the participants who received the vaccine have better control of the virus when the trea...

Today is World AIDS Day – Thanks to everyone working to end AIDS!

by Asphalion

4 years ago
HIVACAR, AIDS, HIV, health, antiretroviral therapy

Today is World AIDS Day and we would like to take this opportunity to increase the awareness on this disease and to thank everyone working tirelessly to end AIDS.

25 years studying the immune system

by IrsiCaixa

5 years ago
HIV, infectious diseases, biomedicine, immune system

The IrsiCaixa AIDS Research Institute celebrates its 25th anniversary as an international center of reference in the field of HIV and infectious diseases. The research at IrsiCaixa is now expanding to...

Predicting the response of HIV-infected individuals to checkpoint inhibitor immunotherapy

by UPF - Universitat Pompeu Fabra

5 years ago
immunotherapy, cancer, HIV

Scientists led by Andreas Meyerhans and Gennady Bocharov have designed a mathematical model to predict the response of HIV-infected individuals to a type of cancer immunotherapy.

WHO recommends an integrase inhibitor as preferred HIV treatment option in all populations

by Fundació Bancària 'la Caixa'

5 years ago
epidemic, HIV, OMS, inhibitor

The WHO Guideline Development Group decided to recomment dolutegravir as the preferred first-line and second-line treatment for all populations, in contrast with initial studies.

Mathematicians calculate the number of immune cells needed to thwart HIV progress

by UPF - Universitat Pompeu Fabra

5 years ago
cells, HIV, infectious diseases, vaccinations

In the future, a model of this kind will enable scientists to carry out computer experiments for the development of vaccines and medicines for infectious diseases. The study, led by Russian researcher...

IrsiCaixa develops antibodies that block one of the internalization pathways of the Ebola virus into human cells

by IrsiCaixa

5 years ago
Ebola, HIV, develops novel antibodies, myeloid cells, protein, serious haemorrhagic disease, vaccines

The study demonstrates that the receptor Siglec-1 is used by different virus, such as Ebola, Marburg and HIV, to enter the myeloid cells and develops novel antibodies against this protein.

Paradigm shift in how bone fractures are avoided in HIV patients

by IMIM - Institut Hospital del Mar d'Investigacions Mèdiques

6 years ago
bone fractures, patients, HIV, chronic infection

The discovery modifies how the problem of bone fracture is addressed in these patients, leading the way to studies of new drugs that complement treatments for combatting the virus