La presencia elevada de un gen empeora el pronóstico del cáncer de pulmón y de páncreas

by CIMA - Centro de Investigación Médica Aplicada

Investigadores del Cima han identificado un gen que está implicado en el desarrollo del cáncer de pulmón y de páncreas. Se trata de un transportador de fosfolípidos (proteínas de las membranas c...

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PNAS. CNIO researchers clarify the role of the two isoforms of KRAS, the most common oncogene in human cancer

by CNIO - Centro Nacional de Investigaciones Oncológicas

KRAS was one of the first oncogenes to be identified, a few decades ago. It is among the most common drivers of cancer and its mutations can be detected in around 25 per cent of human tumours. The dev...

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CNIO researchers develop an effective strategy to induce regression in lung tumours caused by the KRAS oncogene in mice

by CNIO - Centro Nacional de Investigaciones Oncológicas

Researchers from the Experimental Oncology Group at the CNIO have achieved complete remission of 25% of lung tumours caused by the KRAS oncogene in mice by inactivating CDK4 and RAF1, two genes that a...

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CNIO researchers find a potential therapy for the most aggressive type of lung cancer in preclinical models

by CNIO - Centro Nacional de Investigaciones Oncológicas

The specific combination of the drugs dasatinib and demcizumab impairs the growth of KRAS-driven lung tumours, the most aggressive sub-type and with the lowest survival rates

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