IDIBAPS researchers discover a protein that favours diet-induced obesity

by Fundació Clínic per a la Recerca Biomèdica

The inhibition of this molecule, in addition to reducing the predisposition towards developing the disease, also reduces the alteration of the microbiome associated with the obesity.

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A meta-analysis of phase-III trials shows that immunotherapy is more efficacious in liver cancer of viral origin than of nonviral origin

by Fundació Clínic per a la Recerca Biomèdica

Researchers at IDIBAPS have led a study, published in the journal Gastroenterology, in which they analyzed the clinical trials published in the past 20 years on hepatocellular carcinoma (2000-2020) an...

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New key mechanism in the development of non-alcoholic fatty liver disease identified

by CIC bioGUNE

Alterations in neddylation have been shown to be involved in some liver diseases such as liver cancer, fibrosis and cirrhosis, and now in the development of non-alcoholic fatty liver disease. Pharmac...

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Molecular map of hepatocellular carcinoma caused by fatty liver disease revealed

by Fundació Clínic per a la Recerca Biomèdica

IDIBAPS researchers have drafted a molecular map of the most common type of liver cancer, hepatocellular carcinoma, when the origin is fatty liver disease or nonalcoholic steatohepatitis.

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A study in Nature concludes that immunotherapy is less efficacious in nonviral liver cancer

by Fundació Clínic per a la Recerca Biomèdica

An article published in the journal Nature suggests that immunotherapy is effective in patients with HCC of viral origin but does not increase survival of patients with HCC caused by alcohol abuse or ...

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The IT-LIVER European consortium unveils new TGF-beta functions in liver cancer

by IBEC - Institut de Bioenginyeria de Catalunya

Recent research results from the TGF-beta and cancer research group at the Bellvitge Biomedical Research Institute (IDIBELL), within IT-Liver, a collaborative European action among several research gr...

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IDIBAPS researchers identify a new therapeutic target for liver cancer

by IDIBAPS - Institut d'Investigacions Biomèdiques August Pi i Sunyer

IDIBAPS researchers have identified the first epi-driver in liver cancer, a type of epigenetic alteration in the IGF2 gene that causes tumors to grow. In the study, published in the Gastroenterology j...

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CNIO researchers describe inflammatory mechanisms linked to liver cancer

by CNIO - Centro Nacional de Investigaciones Oncológicas

Proinflammatory cytokine IL-17A identified as a key factor in non-alcoholic steatohepatitis, a condition that could lead to hepatocellular carcinoma. Blocking IL-17A could prevent this condition in pa...

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The absence of a protein points out the prognosis of liver cancer patients

by CIMA - Centro de Investigación Médica Aplicada

Using proteome technology, CIMA researchers have established the mechanisms that favor tumor growth and resistance to chemotherapy

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Scientists discover an essential role for a cell signaling pathway that regulates the early stages of liver regeneration and cancer

by IBEC - Institut de Bioenginyeria de Catalunya

The results show, on one hand, that the activation of the EGFR pathway is crucial during the early stages of liver regeneration following surgical resection of a large part of the organ. Indeed, mice ...

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El Clínic participa en un comité de expertos para unificar los criterios radiológicos de diagnóstico en cáncer de hígado

by Fundació Clínic per a la Recerca Biomèdica

Uno de los debates más intensos en oncología hepática es si el diagnóstico por la imagen por sí sólo puede servir o no para determinar si un nódulo en el hígado es maligno o es necesario reali...

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