Scientists build machine learning-based algorithm to predict which cancer patients benefit from immunotherapy

by IRB Barcelona - Instituto de Investigación Biomédica

5 years ago
machine learning, genetic mutations, immune system, immunotherapy, algorithm, protein synthesis

Using machine learning, researchers have built a tool that detects genetic mutations that trigger the immune system, helping identify which cancer patients are more likely to benefit from immunotherap...

A new ribosomal biogenesis regulation point to treat cancer and 5q- syndrome

by IBEC - Institut de Bioenginyeria de Catalunya

7 years ago
free 40S ribosomes, RNA binding protein LARP1, protein synthesis, cancer

Researchers in the Oncobell program at the Bellvitge Biomedical Research Institute (IDIBELL) - Catalan Institute of Oncology (ICO) have unveiled a new role for free 40S ribosomes as guardians of ge...

Scientists discover how the cell stops growing in response to lack of nutrients

by IRB Barcelona - Instituto de Investigación Biomédica

7 years ago
protein synthesis, nutrients, RNA polymerase I, cancer

Researchers unveil a mechanism responsible for halting protein synthesis when cells are deprived of nutrients. The cell regulates its growth by forming various assemblies of RNA polymerase I. The stud...

A comprehensive biotin-based toolbox to study protein homeostasis: A community resource developed by CIC bioGUNE researchers

by CIC bioGUNE

7 years ago
Protein homeostasis, protein synthesis, ubiquitin-like proteins

Protein homeostasis is at the heart of human wellbeing. Numerous diseases such as cancer and neurodegeneration are caused by imbalances in protein synthesis, degradation, and recycling. The family of ...