Driving nano-based approaches closer to the clinic: Vall d’Hebron leads pilot study to assess the efficacy of nanoparticles against pancreatic cancer

by Vall d’Hebron

3 years ago
cancer cells, nanoparticles, pancreatic cancer

Nano-based drug delivery and anti-cancer therapy have shown promise in recent years as potential novel weaponry in the current arsenal of anti-cancer technologies. Nano-driven therapeutics involves th...

A role of colibactin-producing E. coli in carcinogenesis

by IRB Barcelona - Instituto de Investigación Biomédica

4 years ago
epidemiological, cancer cells, carcinogenesis, bacterial

A role of colibactin-producing E. coli in carcinogenesis.

Identification of a determining factor in luminal cancer cells, that cause the greatest number of breast cancer cases

by IRB Barcelona - Instituto de Investigación Biomédica

4 years ago
luminal tumours, cancer cases, cancer cells

Researchers at IRB Barcelona discover a new mechanism in estrogen receptor-positive breast cancer cells. The inhibition of CPEB2, a key factor in the estrogen signalling pathway, causes cancer cells ...

Key gene in familial Alzheimer's disease regulates neuronal development

by Universitat Autònoma de Barcelona (UAB)

5 years ago
Alzheimer, neurodegeneration, cancer cells, neuronal, cancer

The discovery demonstrates that there is a common mechanism between the neurodegeneration occurring in Alzheimer's and the proliferation of cancer cells.

Acidic pH: the weakness of cancer cells

by IRB Barcelona - Instituto de Investigación Biomédica

6 years ago
computational model, cancer cells, intracellular pH

A new computational model has allowed researchers to identify new therapeutic targets that can attack cancer cells by lowering their intracellular pH. The study, which is the result of collaboration b...

Physical forces regulate cell division

by Institut de Bioenginyeria de Catalunya

6 years ago
cell division, epithelial tissues, mechanical forces, cancer cells

This revelation could potentially open avenues to a greater understanding of the uncontrolled proliferation of cancer cells in tumors, and their possible regulation by means of physical forces.

Adenoviruses and the immune system join forces against cancer

by IBEC - Institut de Bioenginyeria de Catalunya

7 years ago
oncolytic adenoviruse, modified viruses, cancer cells, targeted therapy

"We work with oncolytic adenoviruses, viruses that are modified to exclusively attack cancer cells without attacking normal tissue, like a targeted therapy", explains Carlos Fajardo, lead author of th...