BREAST CANCER Despite preclinical data identifying oncogenic RANK pathway activation, the RANK ligand inhibitor denosumab failed to improve outcomes in the neoadjuvant or adjuvant settings

by OncoDNA

Denosumab is a fully human monoclonal antibody that binds to, and inhibits, the receptor activator of RANKL (TNFSF11) and might affect breast cancer biology, as shown by preclinical evidence.

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