How cells decide when to react could shape future treatments for cancer and fibrosis

by IBEC - Institut de Bioenginyeria de Catalunya

2 months ago
vimentin, cancer, fibrosis

It has been discovered that cells do not just sense mechanical forces but also measure how long those forces last before responding. The findings reveal a timing mechanism that allows cells to ignore ...

One of the Possible Causes of Chronic Fatigue in People with Long COVID Identified

by IMIM - Institut Hospital del Mar d'Investigacions Mèdiques

11 months ago
Chronic Fatigue, Long COVID, fibrosis

Fatigue in long COVID patients may be related to fibrosis caused by the infection in the walls of blood vessels. This would hinder the delivery of oxygen to muscle fibers and limit the capacity for pr...

A study reveals sex differences in experimental liver cirrhosis

by Hospital Universitari Germans Trias i Pujol

1 year ago
fibrosis, liver cirrhosis

Researchers at Germans Trias i Pujol Research Institute (IGTP) have led a study that evaluates, for the first time, the difference between sexes in advanced liver disease in a rat model.

Agomab Announces $89 Million Series D Financing, with the participation of Asabys, to Support Broad Fibrosis-focused Pipeline

by Asabys Partners

2 years ago
Agomab Therapeutics, Asabys, Fibrosis, Sanofi, Invus, fibrostenosing Crohn’s disease

Agomab Therapeutics has announced a $89 million Series D financing round, with participation from new investors Sanofi and Invus, as well as existing investors as Asabys.

IRB Barcelona launches a scientific collaboration with Galapagos to identify and validate senolytic drug targets in inflammation and fibrosis

by IRB Barcelona - Instituto de Investigación Biomédica

5 years ago
senolytic drug, fibrosis, degenerative diseases

The Institute for Research in Biomedicine (IRB Barcelona) and the European biotech company Galapagos NV, based in Belgium, have established a scientific collaboration to identify and validate a ser...

Depletion of NOX4 protein improves liver regeneration

by Universitat de Barcelona

5 years ago
NADPH protein, liver, regeneration, fibrosis

The liver is an organ able to regenerate after some damage, since its cells can proliferate and recover the lost or damaged tissue.

Las personas diagnosticadas de esteatosis hepática con fibrosis avanzada presentan mayor riesgo de diabetes e hipertensión

by Fundación Andaluza para la Divulgación de la Innovación y el Conocimiento

6 years ago
hígado graso no alcohólico, esteatosis hepática, fibrosis, diabetes, obesidad, hipertensión, CIBEREHD

Investigadores del CIBEREHD en el Instituto de Biomedicina de Sevilla (IBiS) demuestran que la esteatosis hepática metabólica, o enfermedad del hígado graso no alcohólico, puede jugar un papel cat...

Los antivirales reducen los ingresos por complicaciones asociadas a la Hepatitis C

by Fundació Clínic per a la Recerca Biomèdica

6 years ago
alcohol, antivirales, Hepatitis C, fibrosis

Investigadores del grupo de hepatitis virales del Hospital Clínic -IDIBAPS y del CIBEREHD han publicado en Journal of Hepatology un estudio sobre el impacto que han tenido los antivirales de acción ...

Galecto Raises $64 Million to Accelerate Development of Clinical Pipeline

by Ysios Capital

6 years ago
Eir Ventures, Galecto, Clinical Pipeline, fibrosis, cancer, Soleus Capital

Funds will support preparations for potential EU conditional approval of GB0139 in IPF and multiple new Phase 2 clinical trials

OWL presenta una nueva solución de diagnóstico no invasivo para pacientes con riesgo de sufrir enfermedades hepáticas graves

by OWL Metabolomics

6 years ago
Laboratorios Rubió, test, enfermedades hepáticas, OWL, cirrosis, cáncer hepático, NASH, hígado graso, MASEF score, fibrosis, OWLiverF2+

La compañía biotecnológica vasca OWL ha creado una solución de diagnóstico no invasiva que permite identificar a los pacientes con esteatohepatitis no alcohólica (NASH), una dolencia hepática d...

Descifran un nuevo mecanismo de progresión de la fibrosis en enfermedades hepáticas crónicas

by Fundació Clínic per a la Recerca Biomèdica

6 years ago
hígado, enzima, IDIBAPS, fibrosis, enfermedades hepáticas crónicas

Investigadores del IDIBAPS coordinan un estudio que demuestra el potencial de una nueva estrategia antifibrótica en enfermedades hepáticas crónicas. Se trata del papel de una enzima involucrada en ...

Nuevas tecnologías para trasplantes más seguros

by IrsiCaixa

6 years ago
tecnologías, trasplantes, FIBROKIT, ISCHEMSURG, isquemia, fibrosis

Desde que se realizó con éxito el primer trasplante de un órgano en 1954 –un riñón procedente del hermano gemelo del paciente–, las donaciones de órganos se han vuelto cada vez más habitual...