Mitochondria identified as key player in a rare disease causing microcephaly

by IRB Barcelona - Instituto de Investigación Biomédica

3 months ago
aneuploidies, microcephaly, Mosaic Variegated Aneuploidy (MVA), proteotoxic stress, autophagy

The study has identified the cellular mechanism explaining why certain errors in chromosome division can lead to microcephaly, a condition where the brain develops to a smaller than average size

Centriole instability might contribute to some cases of microcephaly

by IRB Barcelona - Instituto de Investigación Biomédica

5 years ago
Centrioles, γTuRC, microtubules, microcephaly

Researchers at IRB Barcelona identify the γ-tubulin ring complex (or γTuRC) as responsible for providing stability to centrioles. Published in Nature Communications, this study offers a new per

A new way of assessing microcephaly in the context of the Zika virus epidemic

by ISGlobal - Instituto de Salud Global de Barcelona

9 years ago
microcephaly, zika, head circumference, body weight, gestational age

An international team led by Clara Menendez, director of the Maternal, Child and Reproductive Health Initiative at ISGlobal, describes a new way of defining microcephaly based on the ratio between ...