The drug SAR405, the best inhibitor of autophagy

by IRB Lleida. Institut de Recerca Biomèdica

UdL research questions use of 3-methyladenine in studies because of its toxicity

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New pathway to attack tumor cells identified

by CSIC - Centro Superior de Investigaciones Científicas

A study led by researchers from the Institut de Neurociències (INc-UAB), in collaboration with the Institute for Advanced Chemistry of Catalonia (IQAC-CSIC), describes a new mechanism by which the an...

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AbilityPharma publishes full characterization of mechanism of action of ABTL0812, a Phase II clinical inducer of cytotoxic autophagy in cancer cells, in Autophagy journal

by Ability Pharma

The biopharmaceutical company Ability Pharmaceuticals SL announced today that the full description of the mechanism of action of ABTL0812 has been published in the prestigious Autophagy journal (impac...

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COST Action BM1307 PROTEOSTASIS - 'European network to integrate research on intracellular proteolysis pathways in health and disease' – ends in April 2018

by CIC bioGUNE

The COST Action PROTEOSTASIS BM1307, coordinated by Dr. Rosa Barrio (group leader at CIC bioGUNE) ended on the 24th of April 2018. This European network gathered 274 group members from almost all coun...

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IRBLleida researchers open a new door to improve cancer treatment

by IRB Lleida. Institut de Recerca Biomèdica

Researchers at the Pharmacology Unit IRBLleida have trials with several models of cell cultures, including some derived from tumors of patients, exposing them to media without nutrients and trophic fa...

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New mechanism of antitumor action identified

by Vall d’Hebron

By activating the PPAR receptors, ABTL0812 induces over-expression of TRIB3 protein, which binds to the Akt oncogene and inhibits the Akt/mTOR axis.

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