A study by IRBLleida identifies a new therapeutic target for protecting the kidneys in cases of obesity

by IRB Lleida. Institut de Recerca Biomèdica

22 days ago
NMDAR, Chronic kidney disease, obesity

The results show that activation of the NMDA receptor in conditions of excess fat promotes inflammation and oxidative stress in the kidneys

Research, core topic understanding obesity and transforming its treatment

by Universidad de Navarra

3 months ago
GLUT12 protein, molecule Maresin 1, Obesity, sarcopenic obesity

On World Obesity Day, scientists from the Institute of Nutrition and Health at the University of Navarra present research aimed at advancing toward more personalized treatment on a portal

Researchers discover how an anti-obesity drug improves metabolism beyond weight loss

by Universitat de Barcelona

3 months ago
Tirzepatide, obesity, diabetes, brown adipose tissue, GIP and GLP-1

A study in mice shows that the drug has a direct impact on improving metabolism by activating brown adipose tissue, a type of fat specialized in energy expenditure. According to the researchers, thes...

Obesity is not only a weight issue — it is a metabolic and liver disease driver.

by Rubió Metabolomics

6 months ago
Obesity, MASLD, liver fibrosis

In people living with obesity (BMI >30 kg/m²) and type 2 diabetes, the risk of developing MASLD and advanced liver fibrosis increases dramatically, often without symptoms.

A new oral drug for obesity shows positive results in an international study with Vall d’Hebron participation

by Vall d’Hebron

9 months ago
orforglipron, GLP-1 receptor, obesity

The results of a phase 3 clinical trial show that orforglipron reduces body weight by an average of 11% and improves cardiovascular risk factors.

Researchers identify a protein that may help improve the treatment of obesity and cardiovascular disease

by Universitat de Barcelona

12 months ago
Obesity, diabetes, cardiovascular diseases, brown adipose tissue, ACBP protein

The new study, conducted in animal models, describes a repressor factor that blocks brown fat activity: the ACBP protein. Under normal conditions, this protein would regulate when brown fat activity i...

CNIO research identifies a key protein for ‘burning’ fat

by CNIO - Centro Nacional de Investigaciones Oncológicas

1 year ago
MCJ protein, obesity, brown fat

The MCJ protein is key to the fat burning mechanism now identified, making it a promising target for treating obesity, according to the authors in Nature Communications.

Gastric Bypass is a Better Alternative to Reduce Bad Cholesterol Levels in Obesity Surgery Candidates

by IMIM - Institut Hospital del Mar d'Investigacions Mèdiques

2 years ago
Gastric bypass, LDL cholesterol, Obesity

Gastric bypass is more effective than the other common approach, vertical sleeve gastrectomy, in reducing LDL cholesterol levels. This is a common comorbidity in patients undergoing this type of surge...

Research into treatments to combat obesity and excessive sleepiness in children with Prader-Willi syndrome

by Fundació Sant Joan de Déu

2 years ago
Prader-Willi syndrome, obesity, narcolepsy

Researchers from Sant Joan de Déu have promoted various research projects in recent years to advance the understanding of Prader-Willi syndrome and study new treatments for children affected by this ...

Mental disorders tend to occur at association with obesity and allergic conditions in children and young people.

by Universidad de Navarra

4 years ago
Mental disorders, obesity, allergic conditions

A study led by researcher from Institute for Culture and Society combines data derived from the analysis of more than 12 million participants and has found overlap between 10 types of mental disorders...

IDIBAPS researchers discover a protein that favours diet-induced obesity

by Fundació Clínic per a la Recerca Biomèdica

5 years ago
obesity, microbiome, Liver cancer, Research

The inhibition of this molecule, in addition to reducing the predisposition towards developing the disease, also reduces the alteration of the microbiome associated with the obesity.

An IDIBAPS study deciphers abnormalities in mouse neurons that favor obesity

by Fundació Clínic per a la Recerca Biomèdica

5 years ago
Neuronal control, mitochondrial cristae, obesity

The study, led by researchers from the IDIBAPS group Neuronal control of metabolism, has identified the mechanism that favors the onset of obesity in mice by altering the mitochondrial cristae of a ce...