Therapeutic target identified to neutralise toxic forms of Parkinson's-associated protein

by Universitat Autònoma de Barcelona (UAB)

Researchers from the UAB have identified a region in the early aggregates of the alpha-synuclein protein that can be targeted to prevent its conversion into the toxic amyloid fibrils that accumulate i...

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Psychosis in Parkinson’s disease is not only associated with the use of dopaminergic medications, but it is also part of the disease process itself

by Hospital de la Santa Creu i Sant Pau

It has been concluded that psychosis associated with Parkinson’s disease (PDP) not only arises as a complication of dopaminergic drug use but is intimately related to the brain alterations caused by...

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Celtarys Research, USC-biofarma and ZeClinics seek new therapeutic targets for Parkinson's disease and drug candidates that can modulate them

by Asebio

This project, coordinated by Asebio, brings together ZeClinics' target validation and in vivo drug screening capabilities, Celtarys Research's scientific knowledge in fluorescent tool design and synth...

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Sant Pau initiates a pioneering study on the potential benefits of sports in Parkinson’s patients

by Hospital de la Santa Creu i Sant Pau

There are pharmacological treatments and rehabilitation therapies available, it is important to explore complementary approaches that can improve the quality of life of these patients. Interventions b...

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An anticancer drug opens a new path for the treatment of Parkinson’s

by Institute for Advanced Chemistry of Catalonia (IQAC-CSIC)

The fact that M324 is capable of reducing the abnormal accumulation of α-synuclein in neurons derived from stem cells of a Parkinson’s patient, highlights the therapeutic potential of this metaboli...

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Una investigación del Instituto de Biomedicina de Sevilla descubre una proteína clave en el desarrollo de la enfermedad de Parkinson

by Instituto de Biomedicina de Sevilla - IBIS

Investigadore/as del Instituto de Biomedicina de Sevilla (IBiS), en colaboración con la Universidad de Lund (Suecia) y el Imperial College de Londres, han identificado una importante relación entre ...

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Alteraciones en el metabolismo del hígado aportan posibles nuevos biomarcadores de diagnóstico de la enfermedad de Parkinson

by Universidad de Extremadura

Un estudio publicado en la revista Cells describe alteraciones metabólicas en modelos genéticos de la enfermedad asociadas a la enfermedad de Parkinson. Esta investigación colaborativa, liderada de...

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Un nuevo estudio del IBiS esclarece la relación entre la respuesta inflamatoria periférica y la enfermedad de Parkinson

by Instituto de Biomedicina de Sevilla - IBIS

Han demostrado la existencia de una importante relación entre la respuesta inflamatoria, la enfermedad de Parkinson y sus características genéticas. La respuesta inmune inflamatoria periférica es ...

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Un estudio aporta nuevas pistas sobre la toxicidad del hierro en la enfermedad de Parkinson y explica el efecto paradójico de la deferiprona

by Hospital de la Santa Creu i Sant Pau

Un estudio en el que han participado investigadores del Instituto de Investigación del Hospital de la Santa Creu y Sant Pau – IIB Sant Pau concluye que si se administra deferiprona en pacientes que...

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A trial begins with people with Parkinson's disease to improve their mobility

by IRB Lleida. Institut de Recerca Biomèdica

This is a physical exercise training programme funded by the Carlos III Health Institute and led by the Health Cures Research Group (GRECS)

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Possible biomarker for progression of genetic Parkinson disease identified

by Fundació Clínic per a la Recerca Biomèdica

Researchers at Hospital Clínic-IDIBAPS have observed changes in the phosphorylation pattern of certain proteins associated with a mutation in the gene LRRK2, which may make it possible to detect the ...

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Estudio de la progresión de la enfermedad de Parkinson durante 8 años antes del inicio de los síntomas

by Instituto de Investigación Marqués de Valdecilla

Investigadores del grupo de enfermedades neurodegenerativas de IDIVAL y del Servicio de Medicina Nuclear del HUMV, liderados por el Dr. Jon Infante, han publicado los resultados de un estudio llevado ...

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