Human nucleus transcription activity captured at unprecedented nanometric resolution

by Centre for Genomic Regulation

2 years ago
nanometric resolution, RNA, active genes, Human nucleus

Images taken via super-resolution microscopy reveal how the human nucleus organises transcription at much higher resolution than previously possible. According to the authors of a new study in the ...

Identifican la edición del RNA como una vía importante en la progresión del cáncer

by CIBERONC - Centro de Investigación Biomédica en Red, Cáncer

3 years ago
Cancer, diana terapeútica, cáncer tiroides, RNA

Las científicas Julia Ramírez-Moya y Pilar Santisteban pertenecientes al programa de Mecanismos de Progresión Tumoral del CIBERONC, han identificado la edición en el RNA como una vía importante e...

Measuring RNA modifications opens new research avenues for cancer detection

by Centre for Genomic Regulation

3 years ago
RNA, Cancer, ribonucleic acid, Biotechnology

Researchers at the Centre for Genomic Regulation (CRG) have developed a new method to measure the abundance of RNA modifications in much finer detail than previously possible. The findings will adv...

Ageing impairs critical final egg maturation stage

by Centre for Genomic Regulation

3 years ago
fertility, women, RNA

Age may adversely affect women’s fertility by impairing levels of RNA molecules which in turn alter the function of genes involved in key biological pathways during the final maturation stage of ...

Un nuevo mecanismo en la patogenia de la esclerosis lateral amiotrófica (ELA)

by Instituto de Investigación Marqués de Valdecilla

3 years ago
células nerviosas, sistema nervioso, ELA, macromoléculas, RNA, proteinas, función neuronal

La separación de fases líquido-líquido (generar un líquido dentro de otro liquido), como las gotas de aceite en vinagre, es un principio fundamental en la compartimentación y función de las macr...

Researcher Ramon Eritja publishes book about nucleic acids chemistry

by Institute for Advanced Chemistry of Catalonia (IQAC-CSIC)

3 years ago
Ramon Eritja, acids chemistry, drugs, cardiovascular, DNA, RNA

The book “Nucleic Acids Chemistry” takes the most important aspects of the methodology of oligonucleotides synthesis, that is currently expanding by the endorsement of a dozen of new medicines, su...

A study makes a significant contribution to progress in gene therapy efficiency by identifying the source of asymmetry in RNA-DNA hybrids

by IRB Barcelona - Instituto de Investigación Biomédica

5 years ago
DNA, RNA, gene therapies, asymmetry between nucleic acid hybrid

Modesto Orozco’s laboratory (IRB Barcelona) has published a study on the source of asymmetry between nucleic acid hybrid (RNA and DNA) in CHEM (Cell Press). The results are a promising step towards...

The Zika virus in the maternal serum, possible evidence of infection of the foetus

by Vall d’Hebron

7 years ago
Zika virus, RNA, maternal serum, foetus

A study carried out by professionals of Vall d'Hebron Barcelona Hospital Campus notes that the prolonged presence of the Zika virus RNA in maternal serum can be an indicator of infection of the foetus...

Scientists at CIMA discover a gene that is necessary for cellular replication and the structure of the chromosomes

by CIMA - Centro de Investigación Médica Aplicada

8 years ago
DDX11, CONCR, RNA, multiplication of tumor cells

Scientists at the Center for Applied Medical Research (CIMA) at the University of Navarra have discovered CONCR, a long non-coding RNA that regulates cell replication and the formation of the structur...