Klotho: a protein that promotes healthy aging and improves longevity

by Universitat Autònoma de Barcelona (UAB)

An international study led by the Institut de Neurociències at the UAB (INc-UAB) has shown that increasing levels of the Klotho protein in mice extends lifespan and improves both physical and cogniti...

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Design of the first remote photoactivation device

by Universitat de Barcelona

This new device has demonstrated its efficacy in the treatment of pain in a study with a photosensitive molecule derived from morphine, one of the most widely used opioids because of its great analges...

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Descubren cómo una proteína induce cambios tempranos en el cerebro que anticipan el alzhéimer

by CSIC - Centro Superior de Investigaciones Científicas

En condiciones normales, la proteína SFRP1 regula la comunicación entre células durante el desarrollo cerebral. Sin embargo, su acumulación en el cerebro adulto, como ocurre durante procesos infla...

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Investigadores de la UCLM identifican un nuevo mecanismo para revertir déficits de memoria en fases tempranas de la enfermedad de Alzheimer

by Universidad de Castilla-La Mancha

El equipo de la UCLM ha demostrado que la activación farmacológica del S1R con el compuesto PRE-084 es capaz de restaurar la plasticidad sináptica, -es decir, la capacidad del cerebro para adaptars...

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Researchers develop a potential new drug for Alzheimer’s and pain treatment

by Universitat de Barcelona

Researchers of the University of Barcelona led a multidisciplinary team that designed, synthetized and pharmacologically validated these molecules that modulate a therapeutic target which has been lit...

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Sugar-coated nanotherapy dramatically improves neuron survival in Neurodegenerative model

by IBEC - Institut de Bioenginyeria de Catalunya

The new therapy, made of nanofibers and trehalose, a sugar that naturally occurs in plants, traps and neutralizes toxic proteins to stop disease progression. Now trapped, the toxic proteins can no lon...

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¿Cuáles son los tipos de demencia y sus causas?

by Fundación Pasqual Maragall

Algunos tipos de demencia son considerados potencialmente reversibles porque son consecuencia de trastornos que se pueden curar, al menos parcialmente. Por eso, es importante no asumir que una persona...

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Scientists at IBiS establish first mouse model for severe neurodegenerative disease, 100 years after its discovery

by Instituto de Biomedicina de Sevilla - IBIS

The study reveals molecular mechanisms in the rare disease known as adult-onset neuronal ceroid lipofuscinosis and opens new avenues for therapy development.

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New discovery on factors related to Alzheimer’s disease progression

by Universitat de Barcelona

It has been discovered new molecular mechanisms related to the cognitive decline associated with Alzheimer’s disease, the most common dementia. This study, carried out on animal models with the dise...

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Researchers show that a drug for diabetes improves the prognosis of patients undergoing transcatheter aortic valve implantation (TAVI)

by Fundació Clínic per a la Recerca Biomèdica

Conducted in 39 hospitals in Spain with the scientific coordination of the CNIC and in partnership with Hospital Clínic-IDIBAPS, the DapaTAVI study is a milestone in cardiovascular research and could...

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Women Have Greater Capacity to Compensate for Brain Damage in Genetic Frontotemporal Dementia

by Hospital de la Santa Creu i Sant Pau

It has been demonstrated that women who are carriers of genetic mutations causing frontotemporal dementia (FTD) show a greater capacity to compensate for brain damage than men, at least in the early s...

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¿Qué es la neuroplasticidad? La sorprendente flexibilidad del cerebro humano

by Fundación Pasqual Maragall

El Dr. Raffaele Cacciaglia nos ofrece en este artículo una valiosísima explicación de este fascinante fenómeno. Sus líneas de investigación están relacionadas con la conectividad cerebral estru...

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