Ageing-related cardiac disorders such as heart failure and atrial fibrillation often present with intracellular calcium homeostasis dysfunction.

However, knowledge of the intrinsic effects of ageing on cellular calcium handling in the human heart is sparse.

Therefore, this study aimed to analyse how ageing affects key mechanisms that regulate intracellular calcium in human atrial myocytes

Consult the full study: http://cardiovascres.oxfordjournals.org/content/cardiovascres/early/2015/03/09/cvr.cvv046.full.pdf

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