C. elegans as a model to study cancer, in Genetics and Nature Medicine journals

by IBEC - Institut de Bioenginyeria de Catalunya

The nematode Caernorhabditis elegans is used in Dr. Julián Cerón’s laboratory as a model for several diseases. The group has recently published two articles, in Genetics and in Nature medicine.

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New mechanism of antitumor action identified

by Vall d’Hebron

By activating the PPAR receptors, ABTL0812 induces over-expression of TRIB3 protein, which binds to the Akt oncogene and inhibits the Akt/mTOR axis.

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Investigación sobre la relación entre factores ambientales y cáncer

by Universidad de Huelva

Se trata de un estudio a nivel nacional junto al Instituto de Salud Carlos III de Madrid sobre la presencia de metales en los enfermos. La Universidad de Huelva analizará 10.000 muestras de uñas y 3...

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CiQUS researchers describe on ChemBioChem a new prodrug strategy for controlling in vivo cytotoxicity.

by Center for Research in Biological Chemistry and Molecular Materials

One of the biggest challenges in the development of chemotherapeutic agents is to obtain highly selective species that selectively attack tumoral cells while showing low cytotoxicity against normal ce...

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Innovative Approaches to Improve Cancer Patient Outcomes

by Vall d’Hebron

WIN will address the most critical question facing clinical cancer research: Why the improvement of survival still remains limited for most cancer patients?

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New tumor suppressor associates cancer and aging in the hematopoietic system

by Universidad de Oviedo

New research led by the University of Oviedo has identified the protein AIRAPL as a new hematological tumor suppressor. The work published in ‘Nature Medicine' provides new biological keys concernin...

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A new era of research in cancer genomics

by Parc Científic de Barcelona

A study published in the prestigious journal Nature Communications –led by the Centro Nacional de Analisis Genómico (CNAG-CRG), located at the Barcelona Science Park (PCB), and the German Cancer R...

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Researchers find out cause of mutations which are not in genetic material

by IBEC - Institut de Bioenginyeria de Catalunya

The gene identified (referred ADAR1) regulates the level of mutations in RNA, and it is a publisher gene. People with an excess of this gene have an imbalance in the composition of this molecule just ...

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Identificado un nuevo regulador de senescencia celular que podría conectar este proceso con tumorogénesis y organogénesis

by Universidad Autónoma de Madrid

Este trabajo representa un importante avance para conocer mejor el intrincado mecanismo de regulación de senescencia y abre nuevas vías para investigar la conexión de senescencia con otros procesos...

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New anti-carcinogenic compounds with low toxicity that may decrease the side effects of chemotherapy

by Universitat Jaume I

The designed compounds have particularly high therapeutic effects on tumour cells of breast and colon and can be the basis for the development of oncological drugs of low toxicity and high selectivity...

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Active Motif publica un E-book sobre epigenética del cáncer y su relación con la metilación del ADN

by Laboratorios Conda

Active Motif es una empresa especializada en el desarrollo de herramientas innovadoras para la investigación en el campo de la epigenética y la regulación génica que forma parte del catálogo de c...

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Myriad Obtains CE Mark for Tumor BRACAnalysis CDx(TM) and Launches Test in Europe as Companion Diagnostic for PARP Inhibitors

by Myriad Genetics Iberia

Myriad is actively collaborating with leading pharmaceutical companies to develop Tumor BRACAnalysis CDx as a companion diagnostic for use with certain PARP inhibitors, platinum-based drugs and other ...

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