The Epicardial Fat of Patients with Type 2 Diabetes Exerts Negative Effects on Cardiac Cells That Are Reversed in the Presence of ApoJ

by Hospital de la Santa Creu i Sant Pau

The cultured epicardial fat from T2DM patients secretes more atherogenic ceramide species and, in the case of T2DM with coronary disease, more saturated free fatty acids than that of non-diabetic pati...

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Heart toggles between maintenance and energy-boost mode using ribosomes

by Centre for Genomic Regulation

Researchers at the Centre for Genomic Regulation (CRG) in Barcelona have discovered a mechanism involving ribosomes which helps the heart toggle between a ‘regular maintenance mode’ for day-to-day...

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CNIC researchers discover a cell-cleaning system that keeps hearts healthy

by Centro Nacional de Investigaciones Cardiovasculares - CNIC

The study published in Cell shows that macrophages, a type of immune cell, help cardiac cells to get rid of their waste material, and that this maintains the metabolic and contractile properties of th...

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CNIC scientists describe the mechanism of heart regeneration in the zebrafish

by Centro Nacional de Investigaciones Cardiovasculares - CNIC

After a heart attack, the human heart loses millions of cardiomyocytes, the cells that form the muscle wall. In contrast, other animal species have a high regenerative capacity, enabling them to repla...

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Telomere shortening limits the capacity of the heart to regenerate

by Centro Nacional de Investigaciones Cardiovasculares - CNIC

The findings, published in The Journal of Cell Biology (JCB), could point the way to future interventions to increase the regenerative capacity of the mammalian heart. Telomere shortening is one of th...

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