Genomic instability is the main risk factor for tumour development in humans. Therefore understanding its origin and exploring therapeutic targets is paramount. Histone 1 silences a region of the geno...
Read moreResearcher in the field of bioinformatics and genomics Fran Supek is starting his Genome Data Science (aGENDAS) laboratory at the Institute for Research in Biomedicine (IRB Barcelona), within the Str...
Read moreIn epigenetics, there there are “accents”, called DNA methylation, which means having a C or a methyl-C. The first one usually means that a gene is expressed and active, while the second one impli...
Read moreThe study included patients from Hospital Vall d’Hebron and from many other hospitals in different countries like UK, Turkey, Pakistan and Peru. Their DNA was sequenced and the defective gene SGPL1 ...
Read moreUntil recently, genomics was a «read-only» science. But scientists led by Rory Johnson at the University of Bern and the Centre for Genomic Regulation in Barcelona, have now developed a tool for qui...
Read moreThe work, published in the journal Nature Communications, suggests modulator molecules of sliding as possible functional inhibitors. In the long term, the research may help to uncover PCNA inhibitors ...
Read moreGenomic analysis of the Iberian lynx confirms that it is one of the species with the least genetic diversity among individuals, which means that it has little margin for adaptation. The research, whic...
Read moreIn this article, the investigators propose different mechanisms responsible of the resistance to therapy. Cancer stem cells are resistant because are protected at a molecular level by potent detoxific...
Read moreThe new Salk technology is ten times more efficient than other methods at incorporating new DNA into cultures of dividing cells, making it a promising tool for both research and medicine. But, more im...
Read moreScientists at the Singular Research Center Biological and Molecular Materials at the University of Santiago de Compostela (CiQUS) and the University of Birmingham Chemical developed a new and fast met...
Read moreEl grupo de investigación IDIVAL “Biología Celular del Núcleo”, co-liderado por los Profs. Miguel Lafarga y María T. Berciano, con la participación de los miembros del grupo Jorge Mata-Garrid...
Read moreResearchers at the Centre for Genomic Regulation (CRG) are shedding new light on the cell division process, key in embryonic development, and the growth and proliferation of tumors. The study, to be p...
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