The therapeutic target against memory impairments in Down syndrome gains strength

by UPF - Universitat Pompeu Fabra

7 months ago
molecule AEF0217, Down syndrome, cannabinoid receptor 1, neurodegeneration

The experimental, long-term pharmacological treatment in a mice model for Down syndrome to reduce the activity of cannabinoid receptor 1 improves the memory defects associated with the syndrome even w...

Rejuvenating the brain with the help of a computational clock

by CIC bioGUNE

11 months ago
computational clock, neurodegeneration

The study, published in Advanced Science, constitutes a valuable resource to find compounds with therapeutic potential for neurodegenerative diseases.

Researchers describe molecular mechanism involved in Huntington's neurodegeneration

by Universitat de Barcelona

5 years ago
Huntington’s disease, neurons, drugs, neurodegeneration

Protein alteration in the family of lamins causes several diseases, known as laminopathies, such as progeria or precocious ageing.

Minoryx’s preclinical data for leriglitazone in Friedreich’s Ataxia published in Neurobiology of Disease Journal

by Minoryx Therapeutics

6 years ago
therapeutic, neurodegeneration, protection

Preclinical data highlights potential therapeutic action and protection against neurodegeneration

Presented a program capable of automatically detecting neurodegeneration biomarkers through magnetic resonance imaging

by Hospital Universitari de Bellvitge

6 years ago
magnetic resonance, biomakers, neurodegeneration, IDIBELL, UBNeuro, SeSBAT

This tool is able to identify single-person neurodegeneration before the symptom’s appearance, which could significate a more effective and personalized medicine.

Key gene in familial Alzheimer's disease regulates neuronal development

by Universitat Autònoma de Barcelona (UAB)

7 years ago
Alzheimer, neurodegeneration, cancer cells, neuronal, cancer

The discovery demonstrates that there is a common mechanism between the neurodegeneration occurring in Alzheimer's and the proliferation of cancer cells.

Apathy as an indicator of progression in Huntington's disease

by Hospital Universitari de Bellvitge

7 years ago
apathy, Huntington's disease, neurodegeneration

IDIBELL-UB researchers associate changes in white matter connectivity in different subtypes of apathy, one of the most common psychiatric syndromes in Huntington's disease (HD)

Universidad Pablo de Olavide researchers come up with pantothenate kinase-associated therapeutic solution to palliate neurodegeneration

by Universidad Pablo de Olavide, de Sevilla

7 years ago
NACH, PKAN, neurodegeneration, pantothenate kinase-associated

The research of the investigation team led by doctor José Antonio Sánchez Alcázar has been published in the international magazines Molecular Neurobiology and Neural Regeneration Research | PKAN is...

An intellectually active lifestyle protects against neurodegeneration in people with Huntington's disease

by IBEC - Institut de Bioenginyeria de Catalunya

8 years ago
Huntington's disease, intellectually active life, healthy brain, neurodegeneration

The discovery reinforces the importance of leading a cognitively stimulating life to maintain a healthy brain

A treatment increases survival by 50% in mice with Niemann-Pick type C, a rare disease that affects brain and liver

by IDIBAPS - Institut d'Investigacions Biomèdiques August Pi i Sunyer

9 years ago
Niemann-Pick disease type C, rare lysosomal pathology, neurodegeneration, liver function

Researchers from the IIBB-CSIC and the IDIBAPS publish an article in the journal Redox Biology in which they propose an alternative treatment for Niemann-Pick disease type C, a rare lysosomal patholog...