Researchers decypher structure of a human protease implicated in various diseases

by Universitat Autònoma de Barcelona (UAB)

A research led by the IBB-UAB has managed to decypher the structure of the human protease SENP5, implicated in neurodegenerative disorders, cardiovascular diseases and the development of cancer. The r...

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A new horizon in oncology: SUMOylation and its determining role in the evolution of hepatic cancer

by CIC bioGUNE

The study reveals that SUMOylation of HuR, a protein implicated in the post-transcriptional regulation of multiple genes, fosters cancer hallmarks such as proliferation and invasion. Conversely, the a...

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