Latest Blood and lymphatic system biotechnology articles and news on biotech industry leaders, emerging biotech companies in Spain

Una nueva combinación terapéutica mejora la eficacia de la inmunoterapia en tumores sólidos

by CIMA - Centro de Investigación Médica Aplicada

1 year ago
fármaco CM272, tumores sólidos, inmunoterapia, terapias epigenéticas

Investigadores del Cima Universidad de Navarra descubren que la administración de reguladores epigenéticos e inductores de muerte celular prolonga la supervivencia en modelos animales de cáncer

Adding Chemotherapy to Adjuvant Radiotherapy in Advanced Oral Cancer Mainly Benefits Patients With Extensive Extranodal Spread

by Hospital de la Santa Creu i Sant Pau

1 year ago
oral cavity squamous cell carcinoma, Extranodal extension (ENE)

A recent international multicenter study published in JAMA Otolaryngology–Head & Neck Surgery has shown that adding chemotherapy to adjuvant radiotherapy after surgery improves survival outcomes in ...

Investigadores del CIC participan en un proyecto internacional para identificar biomarcadores epigenéticos que detecten precozmente el riesgo de leucemia infantil

by Professional Newco

1 year ago
leucemia infantil, leucemia aguda linfoblástica de células B, epigenética, REACTION

REACTION busca identificar firmas epigenéticas asociadas a la transformación preleucémica, validar estos biomarcadores en muestras de pacientes pediátricos y desarrollar estrategias de intervenci�...

OneChain Immunotherapeutics presents OC-1d, a new cell therapy against leukemia that shows high efficacy and safety in the laboratory

by OneChain Immunotherapeutics

12 months ago
T-cell acute lymphoblastic leukemia (T-ALL), OC-1d, proteins CD1a and CCR9

It has been developed a new cell therapy based on CAR-T cells designed to simultaneously target two specific markers of T-cell acute lymphoblastic leukemia (T-ALL): the proteins CD1a and CCR9.

Científicos del IUOPA de la Universidad de Oviedo descubren una nueva diana inmunológica clave en la leucemia más común en adultos

by Universidad de Oviedo

12 months ago
leucemia linfática crónica, LILRB4

El Grupo de Inmunología Tumoral de la institución académica asturiana identifica una proteína con potencial terapéutico y pronóstico en la leucemia linfática crónica

A Device That Improves the Experience of Patients With Multiple Myeloma, Assessed in a Study With Participation From IDIVAL

by Instituto de Investigación Marqués de Valdecilla

12 months ago
OnBody Delivery System (OBDS)

Nurses Nuria Sánchez and Paula Calvo, from the Clinical Trials Unit of the Marqués de Valdecilla University Hospital (HUMV/IDIVAL), have participated in an international study conducted within the f...

New research points to protecting blood during radiation therapy

by Universidad de Navarra

10 months ago
hematologic toxicity, radiotherapy

University of Navarra scientists develop a pioneering model to measure radiation exposure in blood, paving the way for safer and more precise cancer treatments

ORYZON receives European Medicines Agency approval to initiate a Phase Ib study of iadademstat in sickle cell disease

by Oryzon Genomics

10 months ago
sickle cell disease (SCD), About Iadademstat, β-globin gene, hemoglobin S (HbS)

Oryzon Genomics, a clinical-stage biopharmaceutical company and a European leader in epigenetics, today announced that the European Medicines Agency (EMA) has approved its Clinical Trial Application (...

Study explains how lymphoma rewires human genome

by Centre for Genomic Regulation

10 months ago
cromosomal Translocations, mantle cell lymphoma, IGH enhancer, CCND1 gene, B cells

A study published today in Nucleic Acids Research shows a new way translocations promote cancer. The translocation most typically found in mantle cell lymphoma drags a powerful regulatory element into...

The gut microbiota, key to improving the effectiveness of CAR T-cell therapy in multiple myeloma

by Fundació Clínic per a la Recerca Biomèdica

10 months ago
multiple myeloma, gut microbiota, CAR T-cell therapy

A study led by the Clínic-IDIBAPS reveals that the microbiota can predict and enhance patient response to one of the most innovative immunotherapies against cancer.

Ferran Nadeu is awarded an European Research Council (ERC) starting grant for reconstructing the biological history of chronic lymphocytic leukaemia

by Fundació Clínic per a la Recerca Biomèdica

10 months ago
chronic lymphocytic leukaemia (CLL), CLL-STORY

CLL-STORY aims to reconstruct the complete history of chronic lymphocytic leukaemia (CLL), the most common form of leukaemia in adults. Basic aspects of CLL remain largely unknown even today, such as ...

A new epigenetic methodology makes it possible to reconstruct the evolution of cancer and anticipate its clinical progression

by Fundació Clínic per a la Recerca Biomèdica

10 months ago
fluctuating methylation, epigenetics, EVOFLUx

The research team discovered that the original cell that gave rise to the tumour leaves a unique methylation signature, a fingerprint that not only reveals the identity of the tumour cells, but also c...