New antiviral paves the way to HIV cure: less reservoir, inflammation and chronic immune system activation

by IrsiCaixa

The triple effect of obefazimod would make the drug a potential candidate when designing HIV remission strategies

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Vitamin D receptor inhibition helps prevent vascular calcification in chronic kidney disease and reduce mortality

by IRB Lleida. Institut de Recerca Biomèdica

The novelty of this research is that the vitamin D receptor influences calcification locally, exclusively in the smooth muscle cells of the arteries. These cells are the ones that undergo a phenotypic...

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Investigadores descubren cambios en la microbiota intestinal en pacientes con artritis reumatoide y obesidad

by Fundación Andaluza para la Divulgación de la Innovación y el Conocimiento

Un equipo de investigadores del Hospital Regional Universitario de Málaga y del Hospital Universitario Virgen de la Victoria han publicado un estudio cuyos resultados asocian la bacteria Dialister co...

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New multimorbidity index reveals the importance of fatty acids in the health of the elderly

by Universidad Autónoma de Madrid

A study by the Autonomous University of Madrid (UAM) and CIBERESP has developed a quantitative index to measure multimorbidity. The results, published in The Journals of Gerontology: Series A , highli...

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La cirrosis se asocia a una menor respuesta inmunitaria a las vacunas COVID-19 en pacientes con enfermedad hepática crónica

by CIBEREHD-Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas

De demostró que la capacidad de respuesta global a las vacunas COVID-19 de estos pacientes disminuye cuando presentan cirrosis. La cirrosis, junto con la edad y el tipo de vacuna, se asocia a respues...

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Mineralys Therapeutics Announces Expansion of Planned Phase 2 Trial of Lorundrostat Alone and in Combination with SGLT2 Inhibitor to Treat Patients with Chronic Kidney Disease (CKD)

by Ysios Capital

Mineralys Therapeutics today announced details of an expanded two-part Phase 2 clinical trial for lorundrostat as a potential therapy to treat patients with Stage 2 to 4 chronic kidney disease (CKD), ...

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Babies conceived through assisted reproduction have a much higher risk of being asthmatic, according to a study

by Instituto de Investigación Biosanitaria - Ibs Granada

Babies are also at higher risk of being asthmatic when one of their parents is asthmatic, or when the mother is young at the time of delivery (under 30 years of age).

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Maternal obesity during pregnancy may lead to changes in placental DNA methylation

by IdiBGi

Maternal obesity during pregnancy is known to be associated with an increased risk of chronic diseases in the offspring. Epigenetic mechanisms (those that regulate gene expression), such as DNA methyl...

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Samuel Sánchez Receives ERC Proof of Concept Grant to Target Mucinous Tumors with his Nanorobots

by IBEC - Institut de Bioenginyeria de Catalunya

The “MucOncoBots” project has a primary objective of employing nanobots to transport a specialized drug for the treatment of peritoneal pseudomyxoma (PMP). This rare disease is distinguished by th...

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Primera valoración en humanos de un innovador dispositivo de diálisis para la insuficiencia hepática aguda sobre crónica

by CIBEREHD-Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas

Investigadores del área de enfermedades hepáticas y digestivas del CIBER (CIBEREHD) han participado en el desarrollo de un innovador dispositivo de diálisis hepática para la insuficiencia hepátic...

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Demuestran que la anticoagulación reduce la mortalidad de causa hepática en pacientes con cirrosis y trombosis venosa portal

by CIBERESP - Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública

Los investigadores han colaborado en una revisión sistemática de la información clínica de 500 pacientes con cirrosis y trombosis venosa portal, procedentes de diferentes hospitales europeos y asi...

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A protein is found that reduces liver fibrosis and promotes liver regeneration

by Fundació Clínic per a la Recerca Biomèdica

Led by researchers from IDIBAPS-Hospital Clínic Barcelona, the study shows that the expression of RNF41 in macrophages could be key to solving chronic liver diseases, characterised by inflammation an...

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