Revelan el papel de las vesículas extracelulares del hígado en el desarrollo de la diabetes tipo 2

by CIBERDEM - Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas

Los resultados revelan que las Hep-sEV lipotóxicas inducen una respuesta inflamatoria en el páncreas al ser captadas por los macrófagos de los islotes pancreáticos. Este proceso, mediado por el re...

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Key regions of DNA and genes that trigger liver regeneration have been identified

by IDIBELL - Institut d’Investigació Biomèdica de Bellvitge

It has been identified the regions of DNA that activate the regeneration of this organ. The study, published in the journal Cell Genomics, provides a genome-scale map of the interactions between the r...

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Desarrollan un algoritmo que predice la respuesta al tratamiento en la cirrosis descompensada por hepatitis autoinmune

by CIBEREHD-Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas

Identificar los indicadores clínicos que anticipan el beneficio del tratamiento inmunosupresor en pacientes con cirrosis descompensada causada por hepatitis autoinmune (HAI) ha permitido desarrollar ...

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Descubren que la metástasis hepática desaparece casi por completo cuando se elimina un tipo de célula activada por el cáncer

by Universidad del País Vasco

Los ensayos realizados en ratones muestran que las células estrelladas del hígado, que por sí mismas contribuyen a sanar algunas enfermedades hepáticas, se activan como respuesta al tumor y contri...

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CNIO opens up an avenue to pancreatic cancer prevention

by CNIO - Centro Nacional de Investigaciones Oncológicas

More specifically, the CNIO group has identified a new mechanism that could help explain how a genetic variant in the gene that encodes chemotrypsinogen 2, CTRB2, increases the risk of developing the ...

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Scientific Community Urges Greater Action Against the Silent Rise of Liver Diseases

by ISGlobal - Instituto de Salud Global de Barcelona

In an article published in The Lancet Regional Health Europe, experts warn of the urgent need to improve the detection of chronic liver disease to prevent the growing health impact

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IRB Barcelona leads an international project to investigate resistance to immunotherapy in colorectal cancer metastasis

by IRB Barcelona - Instituto de Investigación Biomédica

The project aims to understand how the metastatic microenvironment evolves over time and why it develops resistance to immunotherapy.

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Identifying a Marker to Determine the Risk of Cancer Recurrence in Patients Undergoing Surgery for Colon or Rectal Tumors

by IMIM - Institut Hospital del Mar d'Investigacions Mèdiques

Having high levels of spermidine, a molecule involved in various cellular processes but also in tumor proliferation, before surgery can increase the risk of recurrence in cases of colon and rectal can...

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The company Rentmultimedia finances the ImmunoCLAUD project

by VHIO

One of the biomarkers that has emerged in the last 2-3 years is Claudin18.2 (CLDN18.2). In the process of oncogenic transformation, this protein migrates to the cell surface, which makes it a potentia...

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They develop a new nanophotonic biosensor for the rapid and accurate detection of Helicobacter pylori

by Instituto de Investigación e Innovación Parc Taulí

It has been developed a biosensor that offers an effective alternative: it allows the rapid and quantitative detection of the bacteria without the need for marker reagents or complex equipment. Using ...

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Researchers design an algorithm to optimise the treatment of patients with decompensated cirrhosis due to autoimmune hepatitis

by Fundació Clínic per a la Recerca Biomèdica

An international study has identified factors that predict which patients with autoimmune hepatitis and decompensated cirrhosis may benefit from immunosuppressive treatment.

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Potential targets are identified for preventive cancer vaccines in Lynch syndrome

by Fundació Clínic per a la Recerca Biomèdica

It has been identified 24 neopeptides that could be good targets for designing preventive cancer vaccines in people with Lynch syndrome. The results show that the selected peptides are repeated among ...

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