Step forward in the understanding of Ewing sarcoma

by IDIBELL - Institut d’Investigació Biomèdica de Bellvitge

IDIBELL researchers identify key factors in Ewing sarcoma metastasis using multi-omics techniques.

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ORYZON announces appointment of Dr. Pierre Beaurang as Strategy and Business Development Advisor

by Oryzon Genomics

Oryzon Genomics S.A., compañía biofarmacéutica de fase clínica centrada en la epigenética para el desarrollo de terapias para enfermedades con importantes necesidades médicas no resueltas, se co...

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ORYZON announces first patient dosed in an Investigator-initiated Phase I study of iadademstat in myelodysplastic syndrome

by Oryzon Genomics

Oryzon Genomics, S.A. announced today that the first patient has been dosed in an investigator-initiated Phase I dose-finding trial of iadademstat, Oryzon’s potent and selective LSD1 inhibitor, in c...

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CNIC scientists discover how the gut modulates the development of inflammatory conditions

by Centro Nacional de Investigaciones Cardiovasculares - CNIC

Scientists at the CNIC have discovered how gut bacteria that cross a weakened intestinal barrier induce changes in bone marrow that strengthen the immune response

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ORYZON to Reshape Its Board of Directors at the Upcoming Shareholders’ Meeting

by Oryzon Genomics

Aimed at enhancing U.S. outreach, investor relations, corporate dialogue, and business development (BD) capabilities

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Maternal stress during pregnancy could leave traces in the placenta that could affect the baby’s development

by Universitat de Barcelona

Maternal stress could leave epigenetic imprints on genes in the placenta associated with cortisol — a necessary hormone for foetal development — and this would affect the baby’s development from...

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Descubren una firma epigenética en pacientes con la enfermedad de la orina de jarabe de arce que altera la metilación del ADN

by Universidad Autónoma de Madrid

Un análisis multi-ómico en fibroblastos de pacientes con la enfermedad de la orina de jarabe de arce (MSUD) descubrió una firma epigenética especifica que afecta la forma en que se regula el ADN. ...

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Un estudio de INCLIVA analiza si las experiencias adversas en la vida temprana generan alteraciones en el tálamo que puedan predisponer a la esquizofrenia

by INCLIVA

La investigación se centra en esta región cerebral, su conectividad y su fisiología para buscar nuevas herramientas terapéuticas y diagnósticas de la esquizofrenia

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Investigadores del IMIBIC descubren cómo una enzima clave en la reparación del ADN participa en la respuesta inmune

by Instituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC)

Este estudio ha revelado que APE1, una proteína característica de mamíferos esencial para mantener la estabilidad del ADN y una diana prometedora para el desarrollo de tratamientos contra el cánce...

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Second-Hand Smoke Exposure During Childhood Leaves its Mark on Children's DNA

by ISGlobal - Instituto de Salud Global de Barcelona

A new study shows that postnatal exposure to tobacco smoke alters DNA methylation, which may help explain adverse health effects

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Having a Biological Age Higher than Chronological Age Increases the Risk of Developing Cancer After a Stroke

by IMIM - Institut Hospital del Mar d'Investigacions Mèdiques

Specifically, for every year of increase in the difference between chronological age (based on birthdate) and biological age (determined by lifestyle habits and exposure to external factors), the risk...

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ORYZON announces journal publication of final Phase IIa REIMAGINE results with vafidemstat in Psychiatry and Clinical Neurosciences

by Oryzon Genomics

The Phase IIa study REIMAGINE evaluated the safety and preliminary efficacy of vafidemstat in agitation/aggression in borderline personality disorder (BPD), attention-deficit/hyperactivity disorder (A...

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