Latest Epigenetics biotechnology articles and news on biotech industry leaders, emerging biotech companies in Spain

How new omics technologies can reveal key cellular and epigenetic mechanisms in chloroplast development

by Centro de Biotecnología y Genómica de Plantas CBGP

5 months ago
Chloroplasts, plastids

A review article published in the Journal of Experimental Botany by CBGP researcher Tamara Hernández-Verdeja reveals the complexity of chloroplast biogenesis and raises questions about spatial and te...

The future of Clinical Trials

by GENESIS Biomed

5 months ago
artificial intelligence (AI), Clinical Trials

Digital transformation and artificial intelligence are redefining the traditional model of clinical trials.

Three Research Projects Advance Understanding of Brain Mechanisms and Address Rare Diseases and Cancer

by Hospital de la Santa Creu i Sant Pau

5 months ago
neuronal synapses and brain oscillations, Fanconi Anemia

Altogether, the projects have been awarded a total granted budget of €1,138,250. The grants will support the launch of new research lines in neuroscience, rare diseases, and cancer, as well as stren...

Epigenetics Influences the Response to Venetoclax in Acute Myeloid Leukemia

by Hospital de la Santa Creu i Sant Pau

5 months ago
Acute myeloid leukemia (AML), Venetoclax, Epigenetics, EIF5A2, hypusination

The integrated data analysis identified a small set of genes whose epigenetic regulation showed a particularly consistent association with sensitivity to venetoclax. Among them, EIF5A2 stood out, as h...

En el Día Mundial contra el Cáncer, CIC bioGUNE subraya el papel de la investigación en metabolismo tumoral frente a la enfermedad

by CIC bioGUNE

5 months ago
metabolismo celular, cáncer, autofagia, hipoxia, glutamina, metionina, glicosilación

Cada 4 de febrero, con motivo del Día Mundial contra el Cáncer, desde CIC bioGUNE se sumamos a la comunidad internacional para concienciar sobre la importancia de la investigación científica en...

ORYZON announces first patient dosed in an Investigator-initiated Phase Ib study of iadademstat in extensive stage small cell lung cancer

by Oryzon Genomics

5 months ago
iadademstat, LSD1 inhibitor, extensive stage small cell lung cancer (ES-SCLC), atezolizumab

Oryzon Genomics announced today that the first patient has been dosed in an investigator-initiated Phase Ib dose-finding trial evaluating iadademstat, Oryzon’s potent and selective LSD1 inhibitor, i...

ORYZON announces appointment of Rolando Gutierrez-Esteinou, M.D., as Chief Medical Officer for CNS

by Oryzon Genomics

5 months ago
Dr. Rolando Gutiérrez-Esteinou

Oryzon Genomics, a clinical-stage biopharmaceutical company and global leader in epigenetics, today announced the appointment of Rolando Gutierrez-Esteinou, M.D., as Chief Medical Officer, CNS Program...

INCLIVA aporta evidencia de que el envejecimiento biológico y la fragilidad son modificables mediante intervenciones de estilo de vida

by INCLIVA

4 months ago
fragilidad, envejecimiento biológico, ejercicio físico, suplementación nutricional

La investigación, cuyos resultados acaban de publicarse en Aging Cell, ha evaluado el impacto de una intervención basada en ejercicio físico supervisado y suplementación nutricional sobre la fragi...

ORYZON receives European Medicines Agency approval to initiate a Phase II study of iadademstat in essential thrombocythemia

by Oryzon Genomics

4 months ago
iadademstat, essential thrombocythemia (ET), Inhibition of LSD1

Oryzon Genomics ha anunciado hoy que la Agencia Europea del Medicamento ha aprobado su Solicitud de Autorización de Ensayo Clínico para iniciar un ensayo clínico de Fase II de iadademstat, el inhi...

Jumping ‘DNA parasites’ linked to early stages of tumour formation

by Centre for Genomic Regulation

4 months ago
LINE-1 (L1) elements, retrotransposition

A study published today in the journal Science reveals how jumping fragments of human DNA, a type of genetic parasite, destabilise the cancer genome.

IDIBELL researchers describe the genetic roadmap that leads from benign thyroid tumours to cancer

by IDIBELL - Institut d’Investigació Biomèdica de Bellvitge

4 months ago
thyroid tumours, miRNAs, DICER1 and DGCR8 genes, MAPK pathway

A multiomic study describes, for the first time, the accumulation of genetic alterations that dictate the malignancy of a type of thyroid tumour, more prevalent in children and young adults.

ORYZON expands patent protection for iadademstat with grant decision in Mexico covering combinations with PD-1/PD-L1 inhibitors

by Oryzon Genomics

4 months ago
small cell lung cancer (SCLC), iadademstat, PD-1/PD-L1 inhibitors

Oryzon Genomics today announced that the Mexican Patent Office has issued a decision to grant for its patent application MX/a/2021/011610, entitled “Combinations of iadademstat for cancer therapy”...